Khat a drug of abuse: roles of free radicals and antioxidants

被引：11

作者：

Aleryani, Samir L. ^{[1
]}

Aleryani, Rowaida A.

Al-Akwa, Ahmed A. ^{[2
]}

机构：

[1] Vanderbilt Univ, Vanderbilt Clin, Nashville, TN 37232 USA

[2] Sanaa Univ, Dept Clin Biochem & Mol Biol, Fac Med & Hlth Sci, Sanaa, Yemen

来源：

DRUG TESTING AND ANALYSIS | 2011年 / 3卷 / 09期

关键词：

Khat; free radicals; reactive oxygen species; reactive nitrogen species; cellular damage; liver; superoxide; CATHA-EDULIS; OXIDATIVE STRESS; GLUTATHIONE DEPLETION; METABOLISM; SCHIZOPHRENIA; PSYCHOSIS;

D O I：

10.1002/dta.224

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Many articles have reviewed the health impact of Khat consumption; however the role of free radicals in the pathogenesis associated with short- and long-term consumption of Khat is absent in the literature. As free radicals and antioxidants converge across various mechanisms in normal physiological function and in disease, this review attempts to uncover the role of endogenous free radicals and the mechanism of cellular injury associated with Khat consumption. Copyright (C) 2010 John Wiley & Sons, Ltd.

引用

页码：548 / 551

页数：4

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