Genome demethylation and imprinting in the endosperm

被引:83
作者
Bauer, Matthew J. [1 ]
Fischer, Robert L. [1 ]
机构
[1] Univ Calif Berkeley, Dept Plant & Microbial Biol, Berkeley, CA 94720 USA
基金
美国国家卫生研究院; 美国国家科学基金会;
关键词
ORIGIN ALLELIC EXPRESSION; MEDEA POLYCOMB GENE; SEED DEVELOPMENT; TRANSPOSABLE ELEMENTS; ARABIDOPSIS ENDOSPERM; MAIZE ENDOSPERM; DNA METHYLATION; EPIGENETIC REGULATION; MOUSE-BRAIN; PHERES1;
D O I
10.1016/j.pbi.2011.02.006
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Imprinting occurs in the endosperm of flowering plants. The endosperm, a product of central cell fertilization, is critical for embryo and seed development. Imprinting in the endosperm is mainly due to the inherited differences in gamete epigenetic composition. Studies have also shown that there are differences in genomic DNA methylation patterns between embryo and endosperm. Examining those differences, along with mutations in the DNA demethylase gene DEMETER, gives insight into the number of imprinted genes and how an antagonistic relationship between TE defense and gene regulation could evolutionarily affect imprinting establishment. Finally, studies demonstrate that DEMETER demethylase activity influences endosperm chromatin composition, and could possibly enhance DNA de novo methylation activity.
引用
收藏
页码:162 / 167
页数:6
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