Determination of prednisone acetate at trace level by flow injection analysis with tris(1,10-phenanthroline) ruthenium(II) chemiluminescence detection

被引：1
作者：
Gong, Pixue [1 ]
Liu, Weihua [2 ]
Liu, Wenwen [1 ]
Du, Kang [1 ]
Liu, Kang [1 ]
Cao, Wei [1 ]
机构：
[1] Univ Jinan, Sch Chem & Chem Engn, Jinan 250022, Peoples R China
[2] Shandong Pesticide Res Inst, Jinan 250100, Peoples R China
来源：
APPLICATION OF CHEMICAL ENGINEERING, PTS 1-3 | 2011年 / 236-238卷
关键词：
Flow injection; Chemiluminescence; Prednisone acetate; Potassium permanganate; Tris(1,10-phenanthroline) ruthenium(II); HUMAN SERUM; CYSTEINE; LUMINOL;
D O I：
10.4028/www.scientific.net/AMR.236-238.2729
中图分类号：
TQ [化学工业];
学科分类号：
0817 ;
摘要：
A simple, sensitive and rapid method for flow injection with chemiluminescence analysis has been developed for the determination of prednisone acetate at trace level. This method is based on the luminescent properties of the tris(1,10-phenanthroline) ruthenium(II)-potassium permanganate -prednisone acetate in acidic medium sensitized by Na2SO3. The optimized experimental conditions are evaluated. Under the optimum experimental conditions, the linear ranges of prednisone acetate are: 4.0x10(-10)similar to 4.0x10(-8) g.mL(-1) and 4.0x10(-8)similar to 2.0x10(-7) g.mL(-1) with a low detection limit is 4.5x10(-11) g.mL(-1) and the relative standard deviation for 1.0x10(-8) g.mL(-1) sample is 1.04% (n=11). The proposed method has been successfully applied to the determination of prednisone acetate in tablets.
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收藏
页码：2729 / +
页数：2
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