Effect of picroliv on rifampicin-induced biochemical changes in the rat liver and serum

被引：0

作者：

Rastogi, R ^{[1
]}

Saksena, S ^{[1
]}

Garg, NK ^{[1
]}

Dhawan, BN ^{[1
]}

机构：

[1] CENT DRUG RES INST,ICMR CTR ADV PHARMACOL RES TRADIT REMEDIES,LUCKNOW 226001,UTTAR PRADESH,INDIA

来源：

PHYTOTHERAPY RESEARCH | 1996年 / 10卷 / 07期

关键词：

hepatoprotection; hepatotoxicity; picroliv; rifampicin;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Rifampicin was administered to rats (50 mg/kg, i.p. daily) for 2, 6, 12 or 24 days and selected biochemical parameters in liver and serum were measured 24h after the last injection, Concomitant administration of picroliv (12 mg/kg) showed maximum hepatoprotective activity in the 6 dag schedule, Administration of picroliv during the recovery phase In 12 and 24 day schedule expedited recovery of most parameters.

引用

页码：610 / 612

页数：3

共 7 条

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[4] DWIVEDI Y, 1991, MED SCI RES, V91, P711
[5] EFFECT OF PICROLIV ON ANTIOXIDANT-SYSTEM IN LIVER OF RATS, AFTER PARTIAL-HEPATECTOMY
RASTOGI, R
SAKSENA, S
GARG, NK
DHAWAN, BN
[J]. PHYTOTHERAPY RESEARCH, 1995, 9 (05) : 364 - 367
[6] RIFAMPICIN INDUCED HEPATOTOXICITY IN RATS - PROTECTIVE EFFECT OF PICROLIV
SAKSENA, S
RASTOGI, R
GARG, NK
DHAWAN, BN
[J]. DRUG DEVELOPMENT RESEARCH, 1994, 33 (01) : 46 - 50
[7] SCHEUER PJ, 1974, LANCET, V1, P421

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