Evidence-Based Somatic Treatment of Depression in Adults

被引：7

作者：

Carlat, Daniel ^{[1
]}

机构：

[1] Tufts Univ, Sch Med, Dept Psychiat, Boston, MA 02111 USA

来源：

PSYCHIATRIC CLINICS OF NORTH AMERICA | 2012年 / 35卷 / 01期

关键词：

Antidepressants; Selective serotonin reuptake inhibitors; Serotonin-norepinephrine reuptake inhibitors; Efficacy studies; STAR-D trial; STAR-ASTERISK-D; ANTIDEPRESSANTS; EFFICACY; METAANALYSIS; VENLAFAXINE; SEVERITY; BENEFITS; TRIALS;

D O I：

10.1016/j.psc.2011.11.002

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

This article reviews recent studies and controversies about the effectiveness of antidepressant medications for depression. It is divided into three broad topics: (1) the heated controversy regarding how one should interpret "efficacy studies" of antidepressants, that is, the standard placebo-controlled double-blind studies used by drug companies to gain Food and Drug Administration approval; (2) "effectiveness studies," open-label studies enrolling types of patients who are excluded from efficacy studies, focusing on one enormous study in particular-the STAR-D trial; and (3) the evidence base that can guide clinicians in the choice of antidepressants for particular patients.

引用

页码：131 / +

页数：13

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