General Mechanism of Actomyosin Contractility

被引：51

作者：

Dasanayake, Nilushi L. ^{[1
]}

Michalski, Paul J. ^{[1
]}

Carlsson, Anders E. ^{[1
]}

机构：

[1] Washington Univ, Dept Phys, St Louis, MO 63130 USA

来源：

PHYSICAL REVIEW LETTERS | 2011年 / 107卷 / 11期

基金：

美国国家卫生研究院;

关键词：

FILAMENTS; NETWORKS;

D O I：

10.1103/PhysRevLett.107.118101

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

Stress generation by myosin minifilaments is analyzed via simulation of their motion in a random actin network. The stresses are overwhelmingly contractile because minifilament equilibrium positions having contractile stress have lower energy than those for expansive stress. Force chains lead to unexpectedly large stresses.

引用

页数：4

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