Cytotoxic effects of sesquiterpene lactones from the flowers of Hemisteptia lyrata B

被引：40

作者：

Ha, TJ

Jang, DS

Lee, JR

Lee, KD

Lee, J

Hwang, SW

Jung, HJ

Nam, SH

Park, KH

Yang, MS ^{[1
]}

机构：

[1] Gyeongsang Natl Univ, Div Appl Sci, Dept Agr Chem, Chinju 660701, South Korea

[2] Gyeongsang Natl Univ, Inst Agr & Life Sci, Chinju 660701, South Korea

[3] Ewha Womans Univ, Grad Sch Mol Life Sci, Seoul 120750, South Korea

[4] Chinju Natl Univ, Dept Food Proc, Chinju 660758, South Korea

来源：

ARCHIVES OF PHARMACAL RESEARCH | 2003年 / 26卷 / 11期

关键词：

Hemisteptia lyrata Bunge; sesquiterpene lactone; aguerin B; 8 alpha-acetoxyzaluzanin C; cynaropicrin; deacylcynaropicrin; cytotoxic activity;

D O I：

10.1007/BF02980201

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Four guaia-12,6-olide type sesquiterpene lactones, aguerin B (1), 8alpha-acetoxyzaluzanin C (2), cynaropicrin (3), and deacylcynaropicrin (4), were isolated from the flowers of Hemisteptia lyrata Bunge. It is the first report on the isolation of compounds 1-4 from Hemisteptia species. All the isolates (1-4) were examined for their cytotoxic activity against SK-OV-3, LOX-IMVI, A549, MCF-7, PC-3, and HCT-15 human cancer cell lines.

引用

页码：925 / 928

页数：4

共 17 条

[1]

[Anonymous], 1977, ENCY TRADITIONAL CHI, P1458

[2] SESQUITERPENE LACTONES OF CONOCEPHALUM-CONICUM [J].