SARS-CoV-2 immunogenicity in individuals infected before and after COVID-19 vaccination: Israel, January-March 2021

被引：1
作者：
Abu Jabal, Kamal [1 ,2 ]
Ben-Amram, Hila [1 ]
Beiruti, Karine [1 ]
Brimat, Ira [1 ,2 ]
Abu Saada, Ashraf [1 ]
Bathish, Younes [1 ]
Sussan, Christian [1 ]
Zarka, Salman [1 ,2 ]
Edelstein, Michael [1 ,2 ]
机构：
[1] Ziv Med Ctr, Safed, Israel
[2] Bar Ilan Univ, Safed, Israel
来源：
EPIDEMIOLOGY AND INFECTION | 2021年 / 149卷
关键词：
COVID-19; Israel; SARS-CoV-2; vaccine immunogenicity; vaccines;
D O I：
10.1017/S0950268821001928
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
Between December 2020 and March 2021, we measured anti-SARS-CoV-2 IgG titres among 725 Israeli hospital workers vaccinated against COVID-19. Infection post-dose 1 vaccination did not increase IgG titres, and individuals infected post-dose 1 had IgG levels comparable to never-infected individuals who received a single dose, lower than fully vaccinated, never-infected individuals. This suggests dose 2, currently not offered to those infected post-dose 1, may be required in these individuals. Larger studies should confirm whether individuals infected post-dose 1 need the second.
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