Metal-Free Reduction of Aromatic Nitro Compounds to Aromatic Amines with B2pin2 in Isopropanol

被引：116

作者：

Lu, Hongtao ^{[1
]}

Geng, Zhiyue ^{[1
]}

Li, Jingya ^{[2
,3
]}

Zou, Dapeng ^{[1
]}

Wu, Yusheng ^{[2
,3
,4
]}

Wu, Yangjie ^{[1
]}

机构：

[1] Zhengzhou Univ, Coll Chem & Mol Engn, Zhengzhou 450052, Peoples R China

[2] Tetranov Biopharm LLC, Zhengzhou 450052, Peoples R China

[3] Collaborat Innovat Ctr New Drug Res & Safety Eval, Zhengzhou 450052, Peoples R China

[4] Tetranov Int Inc, 100 Jersey Ave,Suite A340, New Brunswick, NJ 08901 USA

来源：

ORGANIC LETTERS | 2016年 / 18卷 / 11期

关键词：

TRANSFER HYDROGENATION; NITROARENES; BORON; REACTIVITY; CATALYSTS;

D O I：

10.1021/acs.orglett.6b01274

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A metal-free reduction of aromatic nitro compounds to the corresponding amines has been achieved by a combination of B(2)pin(2) and KOtBu in isopropanol. A series of nitro compounds containing various reducible functional groups were chemoselectively reduced in good to excellent yields.

引用

页码：2774 / 2776

页数：3

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