Axial myopathy due to primary amyloidosis

被引：13

作者：

Friedman, Yael

Paul, John T.

Turley, Jean

Hazrati, Lili-Naz

Munoz, David

机构：

[1] St Michaels Hosp, Div Pathol, Toronto, ON M5B 1W8, Canada

[2] St Michaels Hosp, Div Neurol, Neurophysiol Lab, Toronto, ON M5B 1W8, Canada

[3] Univ Toronto, Fac Med, Div Neurol, Toronto, ON M4X 1K9, Canada

[4] Univ Toronto, Fac Med, Div Lab Med & Pathol, Toronto, ON M4X 1K9, Canada

[5] Oshawa Clin, Oshawa, ON, Canada

来源：

MUSCLE & NERVE | 2007年 / 36卷 / 04期

关键词：

AL amyloidosis; amyloid myopathy; axial myopathy; gammopathy; vasculitis;

D O I：

10.1002/mus.20777

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A 74-year-old man presented with progressive weakness involving only his back muscles. Serum protein electrophoresis revealed the presence of a monoclonal gammopathy. Muscle biopsy of affected muscles demonstrated amyloid light chain deposition surrounding individual muscle fibers as well as in the walls of blood vessels in association with vasculitis. Selective involvement of axial muscles in isolated amyloid myopathy has not been previously described. We report the occurrence of axial myopathy with associated vasculitis as a presenting feature of primary (AL) amyloidosis. Amyloidosis should be considered in the differential diagnosis of focal myopathies, since the condition may be responsive to chemotherapy.

引用

页码：542 / 546

页数：5

共 14 条

[11] CASE OF THE MONTH - AMYLOIDOSIS CAUSING A PROGRESSIVE MYOPATHY [J].