Acute renal failure due to tumor lysis syndrome in a patient with non-Hodgkin's lymphoma

被引：7

作者：

Karagiannis, A ^{[1
]}

Tsorlalis, I ^{[1
]}

Kakafika, A ^{[1
]}

Pateinakis, P ^{[1
]}

Perifanis, V ^{[1
]}

Harsoulis, F ^{[1
]}

机构：

[1] Aristotle Univ Thessaloniki, Sch Med, Hippokration Hosp, Propedeut Dept Int Med 2, Thessaloniki, Greece

来源：

ANNALS OF HEMATOLOGY | 2005年 / 84卷 / 05期

关键词：

acute renal failure; tumor lysis syndrome; non-Hodgkin's lymphoma;

D O I：

10.1007/s00277-004-0984-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Tumor lysis syndrome is characterized by multiple metabolic derangements resulting from the release of intracellular components into the bloodstream due to abrupt malignant cell death, spontaneously or following antineoplastic therapy. The syndrome is characterized by hyperkalemia, hyperuricemia, hyperphosphatemia, and hypocalcemia, while deposition of uric acid and calcium phosphate crystals may result in acute renal failure, which is often exacerbated by concomitant intravascular volume depletion. A case of tumor lysis syndrome complicated by acute renal failure in a patient with non-Hodgkin's lymphoma is reported and the pathophysiology, the clinical features, and the treatment options are discussed.

引用

页码：343 / 346

页数：4

共 20 条

[1] Incidence, medical resource utilisation and costs of hyperuricemia and tumour lysis syndrome in patients with acute leukaemia and non-Hodgkin's lymphoma in four European countries [J].