Management of Cancer Therapy-Associated Oral Mucositis

被引：99

作者：

Brown, Timothy J. ^{[1
]}

Gupta, Arjun ^{[2
]}

机构：

[1] Univ Texas Southwestern Med Ctr Dallas, Dept Internal Med, Dallas, TX USA

[2] Johns Hopkins Univ, Sidney Kimmel Comprehens Canc Ctr, 1650 Orleans St,CRB1 186, Baltimore, MD 21287 USA

来源：

JCO ONCOLOGY PRACTICE | 2020年 / 16卷 / 03期

关键词：

DOUBLE-BLIND; HEAD; RADIATION; PAIN; CHEMOTHERAPY; RADIOTHERAPY; PREVENTION; PLACEBO; TRIAL; COMPLICATIONS;

D O I：

10.1200/JOP.19.00652

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Mucositis is a common and feared complication of anticancer therapy that can affect up to 90% of certain populations of patients with cancer. Even seemingly uncomplicated mucositis, which is often self-limited, can result in intense patient discomfort and decline in quality of life. Severe mucositis can be complicated by uncontrolled pain, superinfection or systemic infection, bleeding, and dehydration, and severe mucositis can lead to interruptions or de-escalation in anticancer treatment, resulting in worse oncologic outcomes. This article provides an evidence-based summary to guide practicing oncologists in the assessment, prevention, and management of mucositis induced by chemotherapy, radiotherapy, and targeted therapy.

引用

页码：103 / 110

页数：8

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