The relationship between hepatitis B virus (HBV) load and levels of transforming growth factor beta 1 (TGF-β1) and soluble Fas (sFas) in human immunodeficiency virus patients with occult HBV infection

被引：1
作者：
de Almeida Silva, Jefferson Luis [1 ]
Vasconcelos De Deus, Dayse Maria [1 ]
Moreira, Regina Celia [2 ]
Lins de Morais, Clarice Neuenschwander [3 ]
Cunha Duarte Coelho, Maria Rosangela [1 ,4 ,5 ]
机构：
[1] Fed Univ Pernambuco UFPE, Div Virol, Keizo Asami Immunopathol Lab LIKA, Recife, PE, Brazil
[2] Adolfo Lutz Inst, Viral Hepatitis Lab, Sao Paulo, Brazil
[3] Ctr Pesquisas Aggeu Magalhaes CPqAM, Dept Immunol, Recife, PE, Brazil
[4] Univ Fed Pernambuco, Dept Physiol & Pharmacol, Ctr Hlth Sci, Recife, PE, Brazil
[5] Univ Fed Pernambuco, Post Grad Program Trop Med, Ctr Hlth Sci, Recife, PE, Brazil
来源：
ARCHIVES OF VIROLOGY | 2015年 / 160卷 / 07期
关键词：
Occult HBV infection; Human immunodeficiency virus; HBV DNA; Transforming growth factor beta 1 (TGF-beta 1); Soluble Fas (sFas); LIVER-DISEASE; EXPRESSION; IL-10;
D O I：
10.1007/s00705-015-2445-8
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The aim of this study was to evaluate the correlation between hepatitis B virus (HBV) load and serum levels of transforming growth factor beta 1 (TGF-beta 1) and soluble Fas (sFas) cytokines in human immunodeficiency virus (HIV) patients who have never been treated with antiretroviral therapy. HBV and hepatitis C virus (HCV) serological markers, sFas and TGF-beta 1 levels, and HBV load were evaluated in 116 patients. While there was no correlation between TGF-beta 1 levels and HBV load, a positive correlation between sFas levels and HBV load was observed in patients with occult HBV infection.
引用
收藏
页码：1801 / 1804
页数：4
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