Rh(III)-Catalyzed Synthesis of 2-Nitro-2H -azirines via sp3 C-H Activation

被引：2

作者：

Huang, Xiaojun ^{[1
]}

Ge, Yun ^{[2
]}

Qian, Yang ^{[3
]}

Zhang, Zhengyu ^{[3
]}

机构：

[1] Nanjing Tech Univ, Coll Mat Sci & Engn, Nanjing 211816, Peoples R China

[2] Nanjing Tech Univ, Sch Chem & Mol Engn, Inst Adv Synth, Nanjing 211816, Peoples R China

[3] Nanjing Tech Univ, Coll Food Sci & Light Ind, Nanjing 211816, Peoples R China

来源：

SYNLETT | 2022年 / 33卷 / 10期

关键词：

Rh(III); 2-nitro-2H-azirine; derivatives; beta-nitrooxime; sp(3) C-H; RING CONTRACTION; INDOLE SYNTHESIS; 2H-AZIRINES; BOND; CYCLOADDITION; EXPANSION; FUNCTIONALIZATION; AMIDATION; ALKYNES;

D O I：

10.1055/a-1804-7546

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An expedient Rh(III)-catalytic method has been described to synthesis of 2-nitro-2H-azirine derivatives from easily accessible beta-nitrooxime ethers via sp(3) C-H activation process. This protocol features of low catalyst loading, very mild reaction conditions, and tolerating a diverse of functionalities in good yields. A possible reaction pathway is proposed involving [RhCp*Cl-2](2)-catalyzed sp(3) C-H bond activation and pivalic acid elimination steps.

引用

页码：969 / 972

页数：4

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