Multifunctional block-copolymer micelle for enhanced delivery of 111In to EGFR-positive breast cancer cells for targeted Auger electron radiotherapy

被引:0
|
作者
Fonge, Humphrey [1 ]
Lee, Helen [1 ]
Reilly, Raymond [1 ]
Allen, Christine [1 ]
机构
[1] Univ Toronto, Dept Pharmaceut Sci, Toronto, ON, Canada
基金
加拿大健康研究院;
关键词
D O I
暂无
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
94
引用
收藏
页数:2
相关论文
共 21 条
  • [1] Multifunctional Block Copolymer Micelles for the Delivery of 111In to EGFR-Positive Breast Cancer Cells for Targeted Auger Electron Radiotherapy
    Fonge, Humphrey
    Lee, Helen
    Reilly, Raymond M.
    Allen, Christine
    MOLECULAR PHARMACEUTICS, 2010, 7 (01) : 177 - 186
  • [2] Amplified delivery of indium-111 to EGFR-positive human breast cancer cells
    Wang, J
    Chen, P
    Su, ZF
    Vallis, K
    Sandhu, J
    Cameron, R
    Hendler, A
    Reilly, RM
    NUCLEAR MEDICINE AND BIOLOGY, 2001, 28 (08) : 895 - 902
  • [3] Block Copolymer Micelles Target Auger Electron Radiotherapy to the Nucleus of HER2-Positive Breast Cancer Cells
    Hoang, Bryan
    Reilly, Raymond M.
    Allen, Christine
    BIOMACROMOLECULES, 2012, 13 (02) : 455 - 465
  • [4] Targeted delivery and enhanced cytotoxicity of cetuximab-saporin by photochemical internalization in EGFR-positive cancer cells
    Yip, Wai Lam
    Weyergang, Anette
    Berg, Kristian
    Tonnesen, Hanne H.
    Selbo, Pal K.
    MOLECULAR PHARMACEUTICS, 2007, 4 (02) : 241 - 251
  • [5] A comparison of non-biologically active truncated EGF (EGFt) and full-length hEGF for delivery of Auger electron-emitting 111In to EGFR-positive breast cancer cells and tumor xenografts in athymic mice
    Panosa, Clara
    Fonge, Humphrey
    Ferrer-Batalle, Montserrat
    Menendez, Javier A.
    Massaguer, Anna
    De Llorens, Rafael
    Reilly, Raymond M.
    NUCLEAR MEDICINE AND BIOLOGY, 2015, 42 (12) : 931 - 938
  • [6] Cisplatin-alginate conjugate liposomes for targeted delivery to EGFR-positive ovarian cancer cells
    Wang, Yunfei
    Zhou, Jinhua
    Qiu, Lihua
    Wang, Xinran
    Chen, Lilan
    Liu, Ting
    Di, Wen
    BIOMATERIALS, 2014, 35 (14) : 4297 - 4309
  • [7] Cytotoxicity of Auger Electron- Emitting [197Hg]Hg-Panitumumab Radioimmunoconjugates on EGFR-Positive Human Breast Cancer Cells
    Chu, Arthur
    Ho, Felix
    Chan, Conrad
    Chen, Shaohuang
    Radchenko, Valery
    Reilly, Raymond
    Davey, Patrick
    JOURNAL OF NUCLEAR MEDICINE, 2024, 65
  • [8] Comparative antiproliferative effects of 111In-DTPA-hEGF, chemotherapeutic agents and γ-radiation on EGFR-positive breast cancer cells
    Chen, P
    Mrkobrada, M
    Vallis, KA
    Cameron, R
    Sandhu, J
    Hendler, A
    Reilly, RM
    NUCLEAR MEDICINE AND BIOLOGY, 2002, 29 (06) : 693 - 699
  • [9] Auger Electron Radioimmunotherapy with 111In-Bn-DTPA-Nimotuzumab Inhibits the Growth of EGFR-Positive Human Breast Cancer Tumours in Mice at Doses that are Non-Toxic to Normal Tissues
    Chan, C.
    Fonge, H.
    Lam, K.
    Reilly, R.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2015, 42 : S314 - S314
  • [10] Novel Auger Electron Radioimmunotherapeutic Agent for HER2-Positive Breast Cancer Cells Composed of Trastuzumab and PAMAM Dendrimer Displaying Multiple DTPA Chelators for 111In
    Chan, C.
    Cai, Z.
    Reilly, R.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2011, 38 : S243 - S244