Magnetic, Luminescent Eu-Doped Mg-Al Layered Double Hydroxide and Its Intercalation for Ibuprofen

被引：41
作者：
Wang, Jun [1 ]
Zhou, Jideng [1 ]
Li, Zhanshuang [1 ]
Song, Yanchao [1 ]
Liu, Qi [1 ]
Jiang, Zhaohua [2 ]
Zhang, Milin [3 ]
机构：
[1] Harbin Engn Univ, Coll Mat Sci & Chem Engn, Harbin 150001, Peoples R China
[2] Harbin Inst Technol, Coll Chem Engn, Harbin 150001, Peoples R China
[3] Minist Educ, Key Lab Superlight Mat & Surface Technol, Harbin 150001, Peoples R China
来源：
CHEMISTRY-A EUROPEAN JOURNAL | 2010年 / 16卷 / 48期
关键词：
aluminum; intercalation; luminescence; magnesium; magnetic properties; ANIONIC CLAYS; DRUG; NANOPARTICLES; HYDROTALCITE; NANOCOMPOSITES; COMPOSITE; RELEASE; IONS; FLUORESCENCE; SURFACE;
D O I：
10.1002/chem.201000602
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A magnetic, luminescent Eu-doped Mg-Al layered double hydroxide with ibuprofen (IBU) intercalated in the gallery has been successfully prepared by a simple coprecipitation method. The physicochemical properties of the samples were well characterized by powder XRD, TEM, FTIR, TGA, inductively coupled plasma MS (ICP-MS), vibrating sample magnetometry (VSM), and fluorospectrophotometry. The results revealed that Fe3O4 nanoparticles are coated on the surface of layered double hydroxides and the obtained ((MgAl0.95EU0.05)-Al-2)Fe- (IBU) sample exhibits both superparamagnetic and luminescent properties, with a saturation magnetization value of 1.86 emu g(-1) and a strong emission band at 610 nm, respectively. Additionally, it was found that the ibuprofen loading amount is about 31% (w/w), and the intercalated ibuprofen possesses sustained release behavior when the magnetic, luminescent composite is immersed in simulated body fluid (SBF).
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页码：14404 / 14411
页数：8
相关论文
共 53 条
  • [1] Effect of gliclazide immobilization into layered double hydroxide on drug release
    Ambrogi, V.
    Perioli, L.
    Ciarnelli, V.
    Nocchetti, M.
    Rossi, C.
    [J]. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2009, 73 (02) : 285 - 291
  • [2] Intercalation compounds of hydrotalcite-like anionic clays with antiinflammatory agents - I. Intercalation and in vitro release of ibuprofen
    Ambrogi, V
    Fardella, G
    Grandolini, G
    Perioli, L
    [J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2001, 220 (1-2) : 23 - 32
  • [3] [Anonymous], ANGEW CHEM, DOI DOI 10.1002/ANGE.200901730
  • [4] Bioinorganic Magnetic Core-Shell Nanocomposites Carrying Antiarthritic Agents: Intercalation of Ibuprofen and Glucuronic Acid into Mg-Al-Layered Double Hydroxides Supported on Magnesium Ferrite
    Ay, Ahmet Nedm
    Zumreoglu-Karan, Birguel
    Temel, Abidin
    Rives, Vicente
    [J]. INORGANIC CHEMISTRY, 2009, 48 (18) : 8871 - 8877
  • [5] Preparation and characterization of intercalation compounds of layered double hydroxides with metallic oxalato complexes
    Beaudot, P
    De Roy, ME
    Besse, JP
    [J]. CHEMISTRY OF MATERIALS, 2004, 16 (05) : 935 - 945
  • [6] New Layered Double Hydroxides/Phospholipid Bilayer Hybrid Material with Strong Potential for Sustained Drug Delivery System
    Begu, Sylvie
    Aubert-Pouessel, Anne
    Polexe, Ramona
    Leitmanova, Eliska
    Lerner, Dan A.
    Devoisselle, Jean-Marie
    Tichit, Didier
    [J]. CHEMISTRY OF MATERIALS, 2009, 21 (13) : 2679 - 2687
  • [7] Fluorescence quenching of single-walled carbon nanotubes in SDBS surfactant suspension by metal ions: Quenching efficiency as a function of metal and nanotube identity
    Brege, Jonathan J.
    Gallaway, Clayton
    Barron, Andrew R.
    [J]. JOURNAL OF PHYSICAL CHEMISTRY C, 2007, 111 (48) : 17812 - 17820
  • [8] On the estimation of average crystallite size of zeolites from the Scherrer equation: A critical evaluation of its application to zeolites with one-dimensional pore systems
    Burton, Allen W.
    Ong, Kenneth
    Rea, Thomas
    Chan, Ignatius Y.
    [J]. MICROPOROUS AND MESOPOROUS MATERIALS, 2009, 117 (1-2) : 75 - 90
  • [9] New hybrid nanostructures based on oxacillin-hydrotalcite-like anionic clays and their textural properties
    Carja, Gabriela
    Kameshima, Yoshizaku
    Ciobanu, Gabriela
    Chiriac, Horia
    Okada, Kiyoshi
    [J]. MICRON, 2009, 40 (01) : 147 - 150
  • [10] Magnetic Resonance Imaging Contrast Agents Based on Iron Oxide Superparamagnetic Ferrofluids
    Casula, Maria F.
    Floris, Patrizia
    Innocenti, Claudia
    Lascialfari, Alessandro
    Marinone, Massimo
    Corti, Maurizio
    Sperling, Ralph A.
    Parak, Wolfgang J.
    Sangregorio, Claudio
    [J]. CHEMISTRY OF MATERIALS, 2010, 22 (05) : 1739 - 1748
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