Overview of studies on metabolic and vascular regulatory changes in early diabetic retinopathy

被引：22
作者：
Alder, VA
Su, EN
Yu, DY
Cringle, S
Yu, P
机构：
[1] Univ Western Australia, Lions Eye Inst, Nedlands, WA 6009, Australia
[2] Univ Western Australia, Ctr Ophthalmol & Visual Sci, Nedlands, WA 6009, Australia
来源：
AUSTRALIAN AND NEW ZEALAND JOURNAL OF OPHTHALMOLOGY | 1998年 / 26卷 / 02期
关键词：
blood flow; diabetic retinopathy; functional changes; oxygen; retinal vasculature;
D O I：
10.1111/j.1442-9071.1998.tb01530.x
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
The present review provides an overview of recent research describing functional changes to the retinal vasculature in very early diabetes. The research focuses on the streptozotocin rat model after 4-6 weeks of induced diabetes and describes functional changes to retinal blood flow, vascular control and retinal oxygenation, as well as a strong vasodilatory response to insulin in the retinal vasculature. The review raises the question of whether choroid dysfunction is also a feature of diabetic retinopathy.
引用
收藏
页码：141 / 148
页数：8
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