On the present and future of dissolution-DNP

被引：184

作者：

Ardenkjaer-Larsen, Jan Henrik ^{[1
,2
]}

机构：

[1] Tech Univ Denmark, Dept Elect Engn, DK-2800 Lyngby, Denmark

[2] GE Healthcare, Brondby, Denmark

来源：

JOURNAL OF MAGNETIC RESONANCE | 2016年 / 264卷

基金：

新加坡国家研究基金会;

关键词：

Dissolution-DNP; Hyperpolarization; Polarizer; DYNAMIC-NUCLEAR-POLARIZATION; NMR SENSITIVITY; PARA-HYDROGEN; PERFORMANCE; INJECTION; RESONANCE; RELAXATION; RADICALS; AGENTS; TIMES;

D O I：

10.1016/j.jmr.2016.01.015

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Dissolution-DNP is a method to create solutions of molecules with nuclear spin polarization close to unity. The many orders of magnitude signal enhancement have enabled many new applications, in particular in vivo MR metabolic imaging. The method relies on solid state dynamic nuclear polarization at low temperature followed by a dissolution to produce the room temperature solution of highly polarized spins. This work describes the present and future of dissolution-DNP in the mind of the author. The article describes some of the current trends in the field as well as outlines some of the areas where new ideas will make an impact. Most certainly, the future will take unpredicted directions, but hopefully the thoughts presented here will stimulate new ideas that can further advance the field. (C) 2016 Elsevier Inc. All rights reserved.

引用

页码：3 / 12

页数：10

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