Cutaneous polyarteritis nodosa in pediatric patients successfully treated with TNF-α inhibitor and methotrexate: Case series and literature review

被引：6

作者：

Do, Ngan ^{[1
]}

Ringold, Sarah ^{[2
]}

Brandling-Bennett, Heather ^{[3
]}

机构：

[1] Univ Washington, Sch Med, Seattle, WA USA

[2] Univ Washington, Dept Pediat, Seattle Childrens Hosp, Div Rheumatol, Seattle, WA 98195 USA

[3] Univ Washington, Dept Pediat, Seattle Childrens Hosp, Div Dermatol, 4800 Sand Point Way NE,M-S OC-9-835, Seattle, WA 98105 USA

来源：

PEDIATRIC DERMATOLOGY | 2019年 / 36卷 / 06期

关键词：

cutaneous polyarteritis nodosa; TNF-alpha Inhibitor; vasculitis; THERAPY;

D O I：

10.1111/pde.14005

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Cutaneous polyarteritis nodosa (CPAN) is a rare necrotizing vasculitis affecting small- to medium-sized arteries. Reported treatments include oral corticosteroids alone or in combination with non-steroidal antiinflammatory drugs, intravenous immunoglobulins, cyclophosphamide, azathioprine, colchicine, or dapsone. However, some patients with CPAN do not respond to such treatments and continue to experience exacerbations over prolonged periods. This series provides support for the use of TNF-alpha inhibitors in the treatment of recalcitrant CPAN in pediatric patients.

引用

页码：932 / 935

页数：4

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