Differential diagnosis and treatment of primary, cutaneous, anaplastic large cell lymphoma: not always an easy task

被引：11

作者：

Diamantidis, Michael D. ^{[1
]}

Papadopoulos, Athanasios ^{[1
]}

Kaiafa, Georgia ^{[1
]}

Ntaios, George ^{[1
]}

Karayannopoulou, Georgia ^{[2
]}

Kostopoulos, Ioannis ^{[2
]}

Girtovitis, Fotios ^{[1
]}

Saouli, Zoi ^{[1
]}

Kontoninas, Zisis ^{[1
]}

Raptis, Ioannis D. ^{[1
]}

Savopoulos, Christos ^{[1
]}

Hatzitolios, Apostolos ^{[1
]}

机构：

[1] Aristotle Univ Thessaloniki, AHEPA Hosp, Propedeut Dept Internal Med 1, Dept Hematol, Thessaloniki 54636, Greece

[2] Aristotle Univ Thessaloniki, Dept Pathol, Thessaloniki 54636, Greece

来源：

INTERNATIONAL JOURNAL OF HEMATOLOGY | 2009年 / 90卷 / 02期

关键词：

Primary; cutaneous; anaplastic large cell lymphoma (PC-ALCL); T-non-Hodgkin lymphoma (T-NHL); CD30(+) lymphoproliferative disorder; Immunohistochemistry; CHOP regimen; CD30(+) LYMPHOPROLIFERATIVE DISORDERS; SECONDARY;

D O I：

10.1007/s12185-009-0365-7

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Primary cutaneous anaplastic large cell lymphoma (PC-ALCL) is a rare and distinct neoplasm appearing de novo on the skin. We present a case of a 75-year-old man diagnosed with PC-ALCL in his left femoral region. We describe the morphology of lesions along with the differential diagnosis, treatment, clinical course and prognosis. We further discuss parameters concerning treatment that should be considered when a PC-ALCL is diagnosed. Our case report demonstrates the complexity in classification, staging, differential diagnosis and therapy selection of PC-ALCLs. It is crucial to emphasize the importance of clinical criteria in diagnosing a PC-ALCL in combination with immunohistochemistry.

引用

页码：226 / 229

页数：4

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