Diagnosis and treatment of laryngopharyngeal reflux

被引：9

作者：

Reichel, O. ^{[1
]}

Hagedorn, H. ^{[1
]}

Berghaus, A. ^{[1
]}

机构：

[1] Univ Munich, Klin Hals Nasen Ohrenheilkunde, Munich, Germany

来源：

LARYNGO-RHINO-OTOLOGIE | 2006年 / 85卷 / 12期

关键词：

laryngopharyngeal reflux; dual-probe PH-monitoring; proton pump inhibitors;

D O I：

10.1055/s-2006-925445

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Background: During the last decades an increased prevalence of reflux disease can be observed. Otolaryngologists play an increasing role in the treatment of patients suffering from laryngopharyngeal reflux (LPR). Typical symptoms for LPR are globus sensation, dysphagia, throat clearing, chronic cough and hoarseness. The most frequent laryngoscopic finding in patients suffering from LPR is a posterior commissure hypertrophy. LPR is confirmed by laryngoscopy, LPR-related laryngoscopy scoring, 24-hour dual-probe pH-monitoring, and by empiric trial with proton pump inhibitors (PPI). For therapy PPI-medication in a dosage of 40 mg BID for at least 3 months is successful in many patients. Additional lifestyle modifications can also have a positive effect. When medical management fails, further diagnostic procedures should be initiated. Conclusion: In patients suffering from unspecific laryngeal and respiratory symptoms LPR is an important differential diagnosis.

引用

页码：919 / 928

页数：10

共 18 条

[11]

KAUFMAN JA, 1995, DIAGNOSIS TREATMENT, P161

[12]

KAUFMAN JA, 1988, J VOICE, V2, P78

[13]

Koufman JA, 1997, OTOLARYNG CLIN N AM, V30, P1

[14] Prevalence of reflux in 113 consecutive patients with laryngeal and voice disorders [J].

Koufman, JA ;

Amin, MR ;

Panetti, M .

OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 2000, 123 (04) :385-388

[15] Gastric acid control with esomeprazole, lansoprazole, omeprazole, pantoprazole, and rabeprazole: A five-way crossover study [J].

Miner, P ;

Katz, PO ;

Chen, YS ;

Sostek, M .

AMERICAN JOURNAL OF GASTROENTEROLOGY, 2003, 98 (12) :2616-2620

[16] Is gastric reflux a cause of otitis media with effusion in children? [J].

Tasker, A ;

Dettmar, PW ;

Panetti, M ;

Koufman, JA ;

Birchall, JP ;

Pearson, JP .

LARYNGOSCOPE, 2002, 112 (11) :1930-1934

[17] Treatment of chronic posterior laryngitis with esomeprazole [J].

Vaezi, MF ;

Richter, JE ;

Stasney, CR ;

Spiegel, JR ;

Iannuzzi, RA ;

Crawley, JA ;

Hwang, C ;

Sostek, MB ;

Shaker, R .

LARYNGOSCOPE, 2006, 116 (02) :254-260

[18] The proximal probe in esophageal pH monitoring: Development of a normative database [J].

Vincent, DA ;

Garrett, JD ;

Radionoff, SL ;

Reussner, LA ;

Stasney, CR .

JOURNAL OF VOICE, 2000, 14 (02) :247-254

← 1 2 →