The cell surface phenotype of human dendritic cells

被引：34

作者：

Clark, Georgina J. ^{[1
,2
]}

Silveira, Pablo A. ^{[1
,2
]}

Hogarth, P. Mark ^{[2
,3
]}

Hart, Derek N. J. ^{[1
,2
]}

机构：

[1] ANZAC Res Inst, Dendrit Cell Res, Gate 3 Hosp Rd, Concord, NSW 2139, Australia

[2] Univ Sydney, Sydney Med Sch, Sydney, NSW, Australia

[3] Burnet Inst, Inflammat Canc & Infect, Melbourne, Vic, Australia

来源：

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY | 2019年 / 86卷

关键词：

Cell surface molecules; Monoclonal antibodies; DC subsets; DC phenotype; CD molecules; HUMAN BLOOD; MONONUCLEAR PHAGOCYTES; ADHESION MOLECULES; CROSS-PRESENTATION; LANGERHANS CELLS; T-LYMPHOCYTES; HUMAN TISSUES; RECEPTOR; ANTIGEN; EXPRESSION;

D O I：

10.1016/j.semcdb.2018.02.013

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Dendritic cells (DC) are bone marrow derived leucocytes that are part of the mononuclear phagocytic system. These are surveillance cells found in all tissues and, as specialised antigen presenting cells, direct immune responses. Membrane molecules on the DC surface form a landscape that defines them as leucocytes and part of the mononuclear phagocytic system, interacts with their environment and directs interactions with other cells. This review describes the DC surface landscape, reflects on the different molecules confirmed to be on their surface and how they provide the basis for manipulation and translation of the potent functions of these cells into new diagnostics and immune therapies for the clinic. (C) 2018 Elsevier Ltd. All rights reserved.

引用

页码：3 / 14

页数：12

共 110 条

[1] Tim-3: An Emerging Target in the Cancer Immunotherapy Landscape [J].

Anderson, Ana C. .

CANCER IMMUNOLOGY RESEARCH, 2014, 2 (05) :393-398

[2] Expression of the membrane protein tyrosine phosphatase CD148 in human tissues [J].

Autschbach, F ;

Palou, E ;

Mechtersheimer, G ;

Rohr, C ;

Pirotto, F ;

Gassler, N ;

Otto, HF ;

Schraven, B ;

Gaya, A .

TISSUE ANTIGENS, 1999, 54 (05) :485-498

[3] Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+ cells as homologues of mouse CD8+ dendritic cells [J].

Bachem, Annabell ;

Guettler, Steffen ;

Hartung, Evelyn ;

Ebstein, Frederic ;

Schaefer, Michael ;

Tannert, Astrid ;

Salama, Abdulgabar ;

Movassaghi, Kamran ;

Opitz, Corinna ;

Mages, Hans W. ;

Henn, Volker ;

Kloetzel, Peter-Michael ;

Gurka, Stephanie ;

Kroczek, Richard A. .

JOURNAL OF EXPERIMENTAL MEDICINE, 2010, 207 (06) :1273-1281

[4] The Interaction Between Signal Regulatory Protein Alpha (SIRPα) and CD47: Structure, Function, and Therapeutic Target [J].

Barclay, A. Neil ;

van den Berg, Timo K. .

ANNUAL REVIEW OF IMMUNOLOGY, VOL 32, 2014, 32 :25-50

[5]

Bates EEM, 1999, J IMMUNOL, V163, P1973

[6] Langerin-expressing dendritic cells in human tissues are related to CD1c+ dendritic cells and distinct from Langerhans cells and CD141high XCR1+ dendritic cells [J].

Bigley, Venetia ;

McGovern, Naomi ;

Milne, Paul ;

Dickinson, Rachel ;

Pagan, Sarah ;

Cookson, Sharon ;

Haniffa, Muzlifah ;

Collin, Matthew .

JOURNAL OF LEUKOCYTE BIOLOGY, 2015, 97 (04) :627-634

[7] DCIR interacts with ligands from both endogenous and pathogenic origin [J].

Bloem, Karien ;

Vuist, Ilona M. ;

van den Berk, Meike ;

Klaver, Elsenoor J. ;

van Die, Irma ;

Knippels, Leon M. J. ;

Garssen, Johan ;

Garcia-Vallejo, Juan J. ;

van Vliet, Sandra J. ;

van Kooyk, Yvette .

IMMUNOLOGY LETTERS, 2014, 158 (1-2) :33-41

[8]

Bouloc A, 2000, EUR J IMMUNOL, V30, P3132, DOI 10.1002/1521-4141(200011)30:11<3132::AID-IMMU3132>3.0.CO

[9]

2-E

[10] LY-A AND LY-B - 2 SYSTEMS OF LYMPHOCYTE ISOANTIGENS IN MOUSE [J].

BOYSE, EA ;

MIYAZAWA, M ;

AOKI, T ;

OLD, LJ .

PROCEEDINGS OF THE ROYAL SOCIETY SERIES B-BIOLOGICAL SCIENCES, 1968, 170 (1019) :175-+

← 1 2 3 4 5 6 7 8 9 10 →