Co-infections in Persons with Early Lyme Disease, New York, USA

被引:30
作者
Wormser, Gary P. [1 ]
McKenna, Donna [1 ]
Scavarda, Carol [1 ]
Cooper, Denise [1 ]
El Khoury, Marc Y. [1 ]
Nowakowski, John [1 ]
Sudhindra, Praveen [1 ]
Ladenheim, Alexander [1 ]
Wang, Guiqing [1 ]
Karmen, Carol L. [1 ]
Demarest, Valerie [2 ]
Dupuis, Alan P., II [2 ]
Wong, Susan J. [2 ]
机构
[1] New York Med Coll, Valhalla, NY 10595 USA
[2] New York State Dept Hlth, Albany, NY USA
关键词
HUMAN GRANULOCYTIC ANAPLASMOSIS; DEER TICK VIRUS; IXODES-SCAPULARIS; HUDSON VALLEY; BABESIOSIS; EHRLICHIOSIS; PREVALENCE; DIVERSITY; DIAGNOSIS; IXODIDAE;
D O I
10.3201/eid2504.181509
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In certain regions of New York state, USA, lxodes scapulads ticks can potentially transmit 4 pathogens in addition to Borrelia burgdorferi: Anaplasma phagocytophilum, Babesia microti, Borrelia miyamotoi, and the deer tick virus subtype of Powassan virus. In a prospective study, we systematically evaluated 52 adult patients with erythema migrans, the most common clinical manifestation of B. burgdorferi infection (Lyme disease), who had not received treatment for Lyme disease. We used serologic testing to evaluate these patients for evidence of co-infection with any of the 4 other tickborne pathogens. Evidence of co-infection was found for B. microti only; 4-6 patients were co-infected with Babesia microti. Nearly 90% of the patients evaluated had no evidence of co-infection. Our finding of B. microti co-infection documents the increasing clinical relevance of this emerging infection.
引用
收藏
页码:748 / 752
页数:5
相关论文
共 24 条
  • [1] Seroprevalence of antibodies that react with Anaplasma phagocytophila, the agent of human granulocytic ehrlichiosis, in different populations in Westchester County, New York
    Aguero-Rosenfeld, ME
    Donnarumma, L
    Zentmaier, L
    Jacob, J
    Frey, M
    Noto, R
    Carbonaro, CA
    Wormser, GP
    [J]. JOURNAL OF CLINICAL MICROBIOLOGY, 2002, 40 (07) : 2612 - 2615
  • [2] Serology of culture-confirmed cases of human granulocytic ehrlichiosis
    Aguero-Rosenfeld, ME
    Kalantarpour, F
    Baluch, M
    Horowitz, HW
    McKenna, DF
    Raffalli, JT
    Hsieh, TC
    Wu, J
    Dumler, JS
    Wormser, GP
    [J]. JOURNAL OF CLINICAL MICROBIOLOGY, 2000, 38 (02) : 635 - 638
  • [3] The Prevalence of Zoonotic Tick-Borne Pathogens in Ixodes Scapularis Collected in the Hudson Valley, New York State
    Aliota, Matthew T.
    Dupuis, Alan P., II
    Wilczek, Michael P.
    Peters, Ryan J.
    Ostfeld, Richard S.
    Kramer, Laura D.
    [J]. VECTOR-BORNE AND ZOONOTIC DISEASES, 2014, 14 (04) : 245 - 250
  • [4] Diversity of Babesia infecting deer ticks (Ixodes dammini)
    Armstrong, PM
    Katavolos, P
    Caporale, DA
    Smith, RP
    Spielman, A
    Telford, SR
    [J]. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 1998, 58 (06) : 739 - 742
  • [5] Isolation of deer tick virus (Powassan virus, lineage II) from Ixodes scapularis and detection of antibody in vertebrate hosts sampled in the Hudson Valley, New York State
    Dupuis, Alan P., II
    Peters, Ryan J.
    Prusinski, Melissa A.
    Falco, Richard C.
    Ostfeld, Richard S.
    Kramer, Laura D.
    [J]. PARASITES & VECTORS, 2013, 6
  • [6] Potential Role of Deer Tick Virus in Powassan Encephalitis Cases in Lyme Disease-endemic Areas of New York, USA
    El Khoury, Marc Y.
    Camargo, Jose F.
    White, Jennifer L.
    Backenson, Bryon P.
    Dupuis, Alan P., II
    Escuyer, Kay L.
    Kramer, Laura
    St George, Kirsten
    Chatterjee, Debarati
    Prusinski, Melissa
    Wormser, Gary P.
    Wong, Susan J.
    [J]. EMERGING INFECTIOUS DISEASES, 2013, 19 (12) : 1926 - 1933
  • [7] Falco RC, 1999, AM J EPIDEMIOL, V149, P771, DOI 10.1093/oxfordjournals.aje.a009886
  • [8] Assessment of Duration of Tick Feeding by the Scutal Index Reduces Need for Antibiotic Prophylaxis After Ixodes scapularis Tick Bites
    Falco, Richard C.
    Daniels, Thomas J.
    Vinci, Vanessa
    McKenna, Donna
    Scavarda, Carol
    Wormser, Gary P.
    [J]. CLINICAL INFECTIOUS DISEASES, 2018, 67 (04) : 614 - 616
  • [9] Co-Infection of Blacklegged Ticks with Babesia microti and Borrelia burgdorferi Is Higher than Expected and Acquired from Small Mammal Hosts
    Hersh, Michelle H.
    Ostfeld, Richard S.
    McHenry, Diana J.
    Tibbetts, Michael
    Brunner, Jesse L.
    Killilea, Mary E.
    LoGiudice, Kathleen
    Schmidt, Kenneth A.
    Keesing, Felicia
    [J]. PLOS ONE, 2014, 9 (06):
  • [10] Lyme Disease Testing by Large Commercial Laboratories in the United States
    Hinckley, Alison F.
    Connally, Neeta P.
    Meek, James I.
    Johnson, Barbara J.
    Kemperman, Melissa M.
    Feldman, Katherine A.
    White, Jennifer L.
    Mead, Paul S.
    [J]. CLINICAL INFECTIOUS DISEASES, 2014, 59 (05) : 676 - 681