Progress in understanding and overcoming biomass recalcitrance: a BioEnergy Science Center (BESC) perspective

被引：22

作者：

Gilna, Paul ^{[1
,2
]}

Lynd, Lee R. ^{[2
,3
]}

Mohnen, Debra ^{[2
,4
,5
]}

Davis, Mark F. ^{[2
,6
]}

Davison, Brian H. ^{[1
,2
]}

机构：

[1] Oak Ridge Natl Lab, BioEnergy Sci Ctr, Oak Ridge, TN 37831 USA

[2] Oak Ridge Natl Lab, Biosci Div, 1 Bethel Valley Rd,Bldg 1505,Rm 100A, Oak Ridge, TN 37831 USA

[3] Dartmouth Coll, Thayer Sch Engn, Hanover, NH 03755 USA

[4] Univ Georgia, Complex Carbohydrate Res Ctr, Athens, GA 30602 USA

[5] Univ Georgia, Dept Biochem & Mol Biol, Athens, GA 30602 USA

[6] Natl Renewable Energy Lab, Natl Bioenergy Ctr, Golden, CO 80401 USA

来源：

BIOTECHNOLOGY FOR BIOFUELS | 2017年 / 10卷

关键词：

Bioconversion; Bioenergy; Recalcitrance; Center operation; Biomass; PLANT-CELL WALLS; REDUCED RECALCITRANCE; DOWN-REGULATION; ETHANOL YIELDS; LIGNIN; CELLULOSE; VARIANTS; PECTIN; SUGAR; BIOSYNTHESIS;

D O I：

10.1186/s13068-017-0971-1

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The DOE BioEnergy Science Center has operated as a virtual center with multiple partners for a decade targeting overcoming biomass recalcitrance. BESC has redefined biomass recalcitrance from an observable phenotype to a better understood and manipulatable fundamental and operational property. These manipulations are the result of deeper biological understanding and can be combined with other advanced biotechnology improvements in biomass conversion to improve bioenergy processes and markets. This article provides an overview of key accomplishments in overcoming recalcitrance via better plants, better microbes, and better tools and combinations. A perspective on the aspects of successful center operation is presented.

引用

页数：7

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