Safety Assessment of Amino Acid Alkyl Amides as Used in Cosmetics

被引：22

作者：

Burnett, Christina L. ^{[1
]}

Heldreth, Bart ^{[1
]}

Bergfeld, Wilma F. ^{[1
]}

Belsito, Donald V. ^{[1
]}

Hill, Ronald A. ^{[1
]}

Klaassen, Curtis D. ^{[1
]}

Liebler, Daniel C. ^{[1
]}

Marks, James G., Jr. ^{[1
]}

Shank, Ronald C. ^{[1
]}

Slaga, Thomas J. ^{[1
]}

Snyder, Paul W. ^{[1
]}

Andersen, F. Alan ^{[1
]}

机构：

[1] Cosmet Ingredient Rev, Suite 1200,1620 L St NW, Washington, DC 20036 USA

来源：

INTERNATIONAL JOURNAL OF TOXICOLOGY | 2017年 / 36卷

关键词：

amino acid alkyl amides; safety; cosmetics;

D O I：

10.1177/1091581816686048

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The Cosmetic Ingredient Review Expert Panel (Panel) reviewed the product use, formulation, and safety data of 115 amino acid alkyl amides, which function as skin and hair conditioning agents and as surfactants-cleansing agents in personal care products. Safety test data on dermal irritation and sensitization for the ingredients with the highest use concentrations, lauroyl lysine and sodium lauroyl glutamate, were reviewed and determined to adequately support the safe use of the ingredients in this report. The Panel concluded that amino acid alkyl amides are safe in the present practices of use and concentration in cosmetics, when formulated to be nonirritating.

引用

页码：17S / 56S

页数：40

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