COVID-19 Vaccination for Persons with Parkinson's Disease: Light at the End of the Tunnel?

被引：21

作者：

Bloem, Bastiaan R. ^{[1
]}

Trenkwalder, Claudia ^{[2
]}

Sanchez-Ferro, Alvaro ^{[3
,4
]}

Kalia, Lorraine V. ^{[5
]}

Alcalay, Roy ^{[6
,7
]}

Chiang, Han-Lin ^{[8
]}

Kang, Un Jung ^{[9
]}

Goetz, Christopher ^{[10
]}

Brundin, Patrik ^{[11
]}

Papa, Stella M. ^{[12
]}

机构：

[1] Radboud Univ Nijmegen, Donders Inst Brain Cognit & Behav, Dept Neurol, Med Ctr, Nijmegen, Netherlands

[2] Univ Med Ctr, Dept Neurosurg, Paracelsus Elena Klin, Kassel, Gottingen, Germany

[3] Hosp Univ HM Puerta, HM CINAC, Madrid, Spain

[4] 12 Octubre Hosp, Madrid, Spain

[5] Univ Toronto, Toronto Western Hosp, Morton & Gloria Shulman Movement Disorders Clin, Div Neurol,Dept Med, Toronto, ON, Canada

[6] Univ Toronto, Toronto Western Hosp, Edmond J Safra Program Parkinsons Dis, Div Neurol,Dept Med, Toronto, ON, Canada

[7] Columbia Univ, Dept Neurol, Irving Med Ctr, New York, NY USA

[8] Taipei Vet Gen Hosp, Neurol Inst, Taipei, Taiwan

[9] NYU, Dept Neurol, Grossman Sch Med, New York, NY 10016 USA

[10] Rush Univ, Sch Med, Dept Neurol, Med Ctr, Chicago, IL 60612 USA

[11] Van Andel Inst, Dept Neurodegenerat Sci, Parkinsons Dis Ctr, Grand Rapids, MI USA

[12] Emory Univ, Sch Med, Dept Neurol, Yerkes Natl Primate Res Ctr, Atlanta, GA 30322 USA

来源：

JOURNAL OF PARKINSONS DISEASE | 2021年 / 11卷 / 01期

关键词：

Parkinson's disease; movement disorders; COVID-19; SARS-CoV-2; pandemic; vaccination; vaccine; efficacy; safety; adverse effects; INFLUENZA;

D O I：

10.3233/JPD-212573

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Several COVID-19 vaccines have recently been approved for emergency use according to governmental immunization programs. The arrival of these vaccines has created hope for people with Parkinson's disease (PD), as this can help to mitigate their risk of becoming infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which can lead to serious, life-threatening disease, at least among those with more advanced PD. However, both persons with PD and physicians looking after these individuals have expressed concerns about the vaccine's efficacy and safety in the specific context of PD and its symptomatic treatment. Here, we discuss our perspective on these concerns, based on our interpretation of the literature plus the unfolding experience with widespread vaccination in the population at large. Because the benefits and risks of COVID-19 vaccines do not appear to be different than in the general population, we recommend COVID-19 vaccination with approved vaccines to persons with PD, unless there is a specific contraindication. Some caution seems warranted in very frail and terminally ill elderly persons with PD living in long-term care facilities.

引用

页码：3 / 8

页数：6

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