Postburn Hypermetabolism: Past, Present, and Future

被引：78

作者：

Jeschke, Marc G. ^{[1
,2
,3
]}

机构：

[1] Sunnybrook Hlth Sci Ctr, Ross Tilley Burn Ctr, 2075 Bayview Ave,Rm D704, Toronto, ON M4N 3M5, Canada

[2] Univ Toronto, Dept Surg, Div Plast Surg, Toronto, ON, Canada

[3] Univ Toronto, Dept Immunol, Toronto, ON, Canada

来源：

JOURNAL OF BURN CARE & RESEARCH | 2016年 / 37卷 / 02期

基金：

美国国家卫生研究院;

关键词：

TRACE-ELEMENT SUPPLEMENTATION; BURNED PEDIATRIC-PATIENTS; GROWTH-HORMONE TREATMENT; FREE FATTY-ACIDS; ENDOPLASMIC-RETICULUM STRESS; RESTING ENERGY-EXPENDITURE; INSULIN-TREATMENT IMPROVES; MUSCLE PROTEIN CATABOLISM; ACUTE-PHASE RESPONSE; GLUCOSE-METABOLISM;

D O I：

10.1097/BCR.0000000000000265

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Hypermetabolism is the ubiquitous response to a severe burn injury, which was first described in the nineteenth century. Despite identification of important components of this complex response, hypermetabolism is still not well understood in its entirety. This article describes this incredibly fascinating response and the understanding we have gained over the past 100 years. Additionally, this article describes novel insights and delineates treatment options to modulate postburn hypermetabolism with the goal to improve outcomes of burn patients.

引用

页码：86 / 96

页数：11

共 153 条

[1]

ABBOTT WE, 1946, SURGERY, V20, P284

[2]

ARORA NS, 1982, AM REV RESPIR DIS, V126, P5

[3] Fatty infiltration of the liver in severely burned pediatric patients: Autopsy findings and clinical implications [J].