BODIPY-based fluorescent probes for mitochondria-targeted cell imaging with superior brightness, low cytotoxicity and high photostability

被引：49

作者：

Gao, Tao ^{[1
,2
,3
,4
]}

He, Huan ^{[1
,2
]}

Huang, Rong ^{[1
,2
]}

Zheng, Mai ^{[1
,2
]}

Wang, Fang-Fang ^{[1
,2
]}

Hu, Yan-Jun ^{[4
]}

Jiang, Feng-Lei ^{[1
,2
]}

Liu, Yi ^{[1
,2
]}

机构：

[1] Wuhan Univ, State Key Lab Virol, Coll Chem & Mol Sci, Wuhan 430072, Peoples R China

[2] Wuhan Univ, Key Lab Analyt Chem Biol & Med, Coll Chem & Mol Sci, Minist Educ, Wuhan 430072, Peoples R China

[3] Hubei Univ Sci & Technol, Sch Nucl Technol & Chem & Biol, Xianning 437100, Peoples R China

[4] Hubei Normal Univ, Hubei Key Lab Pollutant Anal & Reuse Technol, Huangshi 435002, Peoples R China

来源：

DYES AND PIGMENTS | 2017年 / 141卷

基金：

中国国家自然科学基金;

关键词：

Fluorescent probe; Mitochondria; Imaging; Photostability; LIVING CELLS; SELECTIVE DETECTION; HYDROGEN-PEROXIDE; PH; APOPTOSIS; RHODAMINE-123; NANOCLUSTERS; SENSOR; DYES;

D O I：

10.1016/j.dyepig.2017.03.009

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Two mitochondria-targeted fluorescent probes (TPP- and TEA-BODIPY) were rationally designed and easily synthesized. These probes can specifically stain mitochondria in living cells with superior brightness, low cytotoxicity and high photostability, thus are quite promising as mitochondrial tracking probes. (C) 2017 Elsevier Ltd. All rights reserved.

引用

页码：530 / 535

页数：6

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