Utilization of Kidneys With Similar Kidney Donor Risk Index Values From Standard Versus Expanded Criteria Donors

被引:49
作者
Woodside, K. J. [1 ]
Merion, R. M. [2 ,3 ]
Leichtman, A. B. [3 ,4 ]
de los Santos, R. [3 ]
Arrington, C. J. [3 ]
Rao, P. S. [3 ,4 ]
Sung, R. S. [2 ,3 ]
机构
[1] Case Western Reserve Univ, Dept Surg, Cleveland, OH 44106 USA
[2] Univ Michigan, Dept Surg, Ann Arbor, MI 48109 USA
[3] Arbor Res Collaborat Hlth, Ann Arbor, MI USA
[4] Univ Michigan, Dept Internal Med, Ann Arbor, MI 48109 USA
关键词
Expanded criteria donor (ECD); kidney donor risk index (KDRI); kidney transplantation; outcomes; registry; utilization; ORGAN DONATION; UNITED-STATES; TRANSPLANTATION; SURVIVAL; POOL;
D O I
10.1111/j.1600-6143.2012.04146.x
中图分类号
R61 [外科手术学];
学科分类号
摘要
With the shortage of standard criteria donor (SCD) kidneys, efficient expanded criteria donor (ECD) kidney utilization has become more vital. We investigated the effects of the ECD label on kidney recovery, utilization and outcomes. Using data from the Scientific Registry of Transplant Recipients from November 2002 to May 2010, we determined recovery and transplant rates, and modeled discard risk, for kidneys within a range of kidney donor risk index (KDRI) 1.42.1 that included both SCD and ECD kidneys. To further compare similar quality kidneys, these kidneys were again divided into three KDRI intervals. Overall, ECD kidneys had higher recovery rates, but lower transplant rates. However, within each KDRI interval, SCD and ECD kidneys were transplanted at similar rates. Overall, there was increased risk for discard for biopsied kidneys. SCD kidneys in the lower two KDRI intervals had the highest risk of discard if biopsied. Pumped kidneys had a lower risk of discard, which was modulated by KDRI for SCD kidneys but not ECD kidneys. Although overall ECD graft survival was worse than SCD, there were no differences within individual KDRI intervals. Thus, ECD designation adversely affects neither utilization nor outcomes beyond that predicted by KDRI.
引用
收藏
页码:2106 / 2114
页数:9
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