Metal-based new sulfonamides: Design, synthesis, antibacterial, antifungal, and cytotoxic properties

被引：34

作者：

Chohan, Zahid H. ^{[1
]}

Shad, Hazoor A. ^{[1
]}

机构：

[1] Bahauddin Zakariya Univ, Dept Chem, Multan 60800, Pakistan

来源：

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY | 2012年 / 27卷 / 03期

关键词：

Sulfonamides; metal(II) complexes; antibacterial; antifungal; cytotoxic; IN-VITRO ANTIBACTERIAL; SCHIFF-BASES; ZINC(II) COMPLEXES; COPPER(II) COMPLEXES; BIOLOGICAL-PROPERTIES; NICKEL(II); COBALT(II); LIGANDS; NI(II); CU(II);

D O I：

10.3109/14756366.2011.593515

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Cobalt(II), copper(II), nickel(II) and zinc(II) metal complexes with 5-chlorosalicyladehyde derived Schiff base sulfonamides have been synthesized and characterized. Structure and bonding nature of all the synthesized compounds have been deduced from physical, analytical, and spectral (IR, H-1 NMR, C-13 NMR, Mass, electronic) data. An octahedral geometry has been proposed for all the metal complexes. The ligands and their metal complexes have been screened for their in vitro antibacterial, antifungal, and cytotoxic properties and results are reported.

引用

页码：403 / 412

页数：10

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