An efficient one-pot synthesis of substituted 2-aminobenzo-1-thiophene-3-carbonitriles

被引：4
|
作者：
Krishnananthan, Subramaniarri [1 ]
Smith, Daniel [1 ]
Traeger, Sarah C. [1 ]
Mathur, Arvind [1 ]
Li, Jianqing [1 ]
机构：
[1] Bristol Myers Squibb Co, Dept Discovery Synth, Princeton, NJ 08543 USA
来源：
TETRAHEDRON LETTERS | 2015年 / 56卷 / 24期
关键词：
One-pot synthesis; Intramolecular cyclization; 2-Aminol-benzothiophene-3-carbonitriles2-(2-fluorophenyl)acetonitriles; O-Ethyl carbonisothiocyanatidate;
D O I：
10.1016/j.tetlet.2015.04.048
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient one-pot synthesis of substituted 2-aminobenzo-1-thiophene-3-carbonitriles from substituted 2-(2-fluorophenyl)acetonitriles and O-ethyl carbonisothiocyanatidate in moderate to good yields was described. (C) 2015 Elsevier Ltd. All rights reserved.
引用
收藏
页码：3766 / 3768
页数：3
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