Randomized trial comparing overnight preoperative fasting period Vs oral administration of apple juice at 06:00-06:30 AM in pediatric orthopedic surgical patients

Background: We aimed to evaluate the efficacy of clear liquids orally administered at 06:00-06:30 AM on the morning of surgery to reduce prolonged preoperative fasting periods. Methods : After obtaining informed parental consent, 100 children undergoing scheduled orthopedic surgical procedures, ASA I-II, were randomly allocated to two groups. In group 1, children underwent the typical overnight preoperative period and patients in group 2 received a commercial brand of apple juice (glucose 28 g in 250 ml) at 06:00-06:30 AM on the day of surgery. Patients < 3 years old received 15 ml.kg(-1) and older children 10 ml.kg(-1) to a maximum volume of 250 ml. All patients underwent overnight fasting for milk and solids. Results: Fasting time was 4.8 +/- 2.1 h (ranging from 3 to 11 h) in the group receiving apple juice at 06:00-06:30 AM and 13.2 +/- 3.3 h (ranging from 5 to 19 h) in the overnight-fasting group (P < 0.05; 95% CI: -9.6 to -7.4 h). More patients were irritable (odds ratio, OR 4.5; 95% CI: 1.9-10.8) and dehydrated (OR 21.6; 95% CI: 5.9-79.0) in the overnight-fasting group. Glucose levels < 2.7 mmol.l(-1) (50 mg.dl(-1)) were not reported in any case. Conclusions: A 15 ml.kg(-1) of apple juice for patients of < 3 years of age or 10 ml.kg(-1) for older children, at 06:00-06:30 AM of the surgical morning is a simple procedure to prevent dehydration and to produce positive behavior in low-risk, pediatric surgical patients.