13C NMR spectroscopic studies of the behaviors of carbonyl compounds in various solutions

C-13 NMR spectroscopic studies were performed for carbonyl compounds having a hydroxyl group, a carboalkoxy group, an acetoxy group, or a carboxyl group in various solvents with different polarities for observation of their behaviors of C-13 NMR chemical shifts of carbonyl carbons in solutions. It was found that the chemical shifts of the carbonyl carbons in C-13 NMR have good correlation with the empirical parameter for solvent polarities, al, depending on the structures. Inter-or intramolecular hydrogen bonding and dipolar-dipolar interactions appear to play a key role in this observation. (C) 2017 Elsevier Ltd. All rights reserved.