Numerical Study of Temperature Distribution in a Spherical Tissue in Magnetic Fluid Hyperthermia Using Lattice Boltzmann Method

被引：38

作者：

Lahonian, Mansour ^{[1
]}

Golneshan, Ali Akbar ^{[2
]}

机构：

[1] Kurdistan Univ, Dept Mech Engn, Sanandaj, Iran

[2] Shiraz Univ, Fac Mech Engn, Shiraz, Iran

来源：

IEEE TRANSACTIONS ON NANOBIOSCIENCE | 2011年 / 10卷 / 04期

关键词：

Bio-heat equation; lattice Boltzmann method; magnetic field; magnetic fluid hyperthermia; magnetic nanoparticle; HEAT-TRANSFER; SKIN SURFACE; NANOPARTICLES; CONDUCTION; MODEL; EQUATION; FLOWS; MFH;

D O I：

10.1109/TNB.2011.2177100

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

This work applies a three-dimensional lattice Boltzmann method (LBM), to solve the Pennes bio-heat equation (BHE), in order to predict the temperature distribution in a spherical tissue, with blood perfusion, metabolism and magnetic nanoparticles (MNPs) heat sources, during magnetic fluid hyperthermia (MFH). So, heat dissipation of MNPs under an alternating magnetic field has been studied and effect of different factors such as induction and frequency of magnetic field and volume fraction of MNPs has been investigated. Then, effect of MNPs dispersion on temperature distribution inside tumor and its surrounding healthy tissue has been shown. Also, effect of blood perfusion, thermal conductivity of tumor, frequency and amplitude of magnetic field on temperature distribution has been explained. Results show that the LBM has a good accuracy to solve the bio-heat transfer problems.

引用

页码：262 / 268

页数：7

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