Genomics in Pediatric Endocrinology-Genetic Disorders and New Techniques

被引：1

作者：

Tenore, Alfred ^{[1
]}

Driul, Daniela ^{[1
]}

机构：

[1] Univ Udine, Div Pediat Endocrinol, Dept Pediat DPMSC, Sch Med, I-33100 Udine, Italy

来源：

PEDIATRIC CLINICS OF NORTH AMERICA | 2011年 / 58卷 / 05期

关键词：

Genomics; Hormones; Pediatric endocrinology; Positional cloning; DNA microarray; GROWTH-HORMONE; RECEPTOR GENE; MOLECULAR-BASIS; NEOPLASIA TYPE-1; G-PROTEIN; MUTATIONS; SUSCEPTIBILITY; THERAPY; DEFICIENCY; MECHANISMS;

D O I：

10.1016/j.pcl.2011.07.001

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

In the last few years, there have been remarkable advances in the development of new and more sophisticated genetic techniques. These have allowed a better understanding of the molecular mechanisms of genetically determined pediatric endocrine disorders and are paving the way for a radical change in diagnosis and treatment. This article introduces some of these concepts and some of the genetic techniques being used.

引用

页码：1061 / +

页数：22

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