Interferon-alfa treatment of essential thrombocythemia during pregnancy

被引:11
作者
Iwashita, Toshiko [2 ]
Fujitani, Mayumi [2 ]
Yamamoto, Yoshiaki [2 ]
Katsurada, Tatsuya [1 ]
Yoshida, Yataro [1 ]
机构
[1] Takeda Gen Hosp, Dept Hematol, Fushimi Ku, Kyoto 6011495, Japan
[2] Takeda Gen Hosp, Dept Obstet & Gynecol, Kyoto 6011495, Japan
关键词
essential thrombocythemia; pregnancy; interferon-alfa;
D O I
10.2169/internalmedicine.45.1879
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We report on 2 successful pregnancies in a young woman who has essential thrombocythemia. The platelet count remained well controlled with interferon-alfa administration together with acetylsalicylic acid in each pregnancy. The present case and the published series suggest that close monitoring of the platelet count is crucial and that interferon may be the preferred therapeutic option in the management of pregnancy in patients with essential thrombocythemia.
引用
收藏
页码:1161 / 1164
页数:4
相关论文
共 50 条
[21]   Alfa-interferon in the treatment of essential thrombocythemia: clinical results and evaluation of its biological effects on the hematopoietic neoplastic clone [J].
Sacchi, S ;
Gugliotta, L ;
Papineschi, F ;
Liberati, AM ;
Rupoli, S ;
Delfini, C ;
Ruggeri, M ;
Cavanna, L ;
Bucalossi, A ;
Benedetti, E ;
Ferrandina, C ;
Vinci, G ;
Morselli, M ;
Torelli, G .
LEUKEMIA, 1998, 12 (03) :289-294
[22]   Successful maternal and fetal outcome in a rare case of essential Thrombocythemia with pregnancy using Interferon alpha [J].
Singh, Neeta ;
Kumar, Sunesh ;
Roy, K. K. ;
Sharma, Vaishali ;
Jalak, Ashish .
PLATELETS, 2012, 23 (04) :319-321
[23]   Treatment of indolent primary cutaneous B-cell lymphomas with subcutaneous interferon-alfa [J].
Vandersee, Staffan ;
Terhorst, Dorothea ;
Humme, Daniel ;
Beyer, Marc .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2014, 70 (04) :709-715
[24]   Periodic plateletpheresis during pregnancy in a high-risk patient with essential thrombocythemia [J].
Yamaguchi, Koushi ;
Hisano, Michi ;
Sakata, Mariko ;
Minatogawa, Yasuyuki ;
Suzuki, Teruaki ;
Ozawa, Nobuaki ;
Kitagawa, Michihiro ;
Murashima, Atsuko .
JOURNAL OF CLINICAL APHERESIS, 2006, 21 (04) :256-259
[25]   ESSENTIAL THROMBOCYTHEMIA IN PREGNANCY - REPORT OF 4 CASES [J].
RADAELLI, F ;
COLOMBI, M ;
MAIOLO, AT .
HAEMATOLOGICA, 1994, 79 (04) :360-363
[26]   Interferon therapy for pregnant patients with essential thrombocythemia in Japan [J].
Edahiro, Yoko ;
Yasuda, Hajime ;
Gotoh, Akihiko ;
Morishita, Soji ;
Suzuki, Toshifumi ;
Takeda, Jun ;
Ando, Jun ;
Tsutsui, Miyuki ;
Itakura, Atsuo ;
Komatsu, Norio .
INTERNATIONAL JOURNAL OF HEMATOLOGY, 2021, 113 (01) :106-111
[27]   Interdisciplinary management recommendations for toxicity associated with interferon-alfa therapy [J].
Hauschild, Axel ;
Kaehler, Katharina C. ;
Schaefer, Martin ;
Fluck, Michael .
JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 2008, 6 (10) :829-837
[28]   Interferon therapy for pregnant patients with essential thrombocythemia in Japan [J].
Yoko Edahiro ;
Hajime Yasuda ;
Akihiko Gotoh ;
Soji Morishita ;
Toshifumi Suzuki ;
Jun Takeda ;
Jun Ando ;
Miyuki Tsutsui ;
Atsuo Itakura ;
Norio Komatsu .
International Journal of Hematology, 2021, 113 :106-111
[29]   RECOMBINANT INTERFERON-ALPHA-2B AS TREATMENT OF ESSENTIAL THROMBOCYTHEMIA [J].
RAMETTA, V ;
FERRARA, F ;
MAROTTOLI, V ;
MATERA, C ;
METTIVIER, V ;
CIMINO, R .
ACTA HAEMATOLOGICA, 1994, 91 (03) :126-129
[30]   Peginterferon alfa-2a monotherapy in essential thrombocythemia [J].
Mechelfekh, Yaquine ;
Requena, Gaspar Aspas .
BULLETIN DU CANCER, 2025, 112 (02) :115-116