Bronchiectasis: New Approaches to Diagnosis and Management

被引:20
作者
Feldman, Charles [1 ]
机构
[1] Univ Witwatersrand, Charlotte Maxeke Johannesburg Acad Hosp, Fac Hlth Sci, Div Pulmonol,Dept Internal Med, ZA-2913 Johannesburg, South Africa
关键词
Bronchiectasis; Corticosteroids; High-resolution CT scan; Macrolides; Physiotherapy; Vaccination; CYSTIC FIBROSIS BRONCHIECTASIS; NON-CF BRONCHIECTASIS; QUALITY-OF-LIFE; CHRONIC BRONCHIAL INFECTION; MACROLIDE THERAPY; LONG-TERM; SURGICAL-MANAGEMENT; PSEUDOMONAS-AERUGINOSA; INHALED CORTICOSTEROIDS; PURULENT BRONCHIECTASIS;
D O I
10.1016/j.ccm.2011.05.002
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Non-cystic fibrosis (CF) bronchiectasis is a common, potentially serious, condition. Further investigations should be performed in an attempt to identify the underlying cause because it may lead to a change in therapy and have significant prognostic implications. MRI is being investigated as a radiation free alternative to high-resolution CT scan of the chest. Many of the treatment recommendations for non-CF bronchiectasis have not been studied in randomized controlled trials but have been extrapolated from the management recommendations for CF. Studies are beginning to inform decisions regarding the management of non-CF bronchiectasis, and an understanding of the best treatment options is beginning to emerge.
引用
收藏
页码:535 / +
页数:13
相关论文
共 101 条
[21]  
CURRIE DC, 1990, Q J MED, V76, P799
[22]  
Cymbala Alicia A, 2005, Treat Respir Med, V4, P117, DOI 10.2165/00151829-200504020-00005
[23]  
Dagli E, 2000, Paediatr Respir Rev, V1, P64, DOI 10.1053/prrv.2000.0011
[24]  
Davies G, 2004, THORAX, V59, P540
[25]   Effect of increasing doses of mannitol on mucus clearance in patients with bronchiectasis [J].
Daviskas, E. ;
Anderson, S. D. ;
Eberl, S. ;
Young, I. H. .
EUROPEAN RESPIRATORY JOURNAL, 2008, 31 (04) :765-772
[26]   Inhalation of dry powder mannitol improves clearance of mucus in patients with bronchiectasis [J].
Daviskas, E ;
Anderson, SD ;
Eberl, S ;
Chan, HK ;
Bautovich, G .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1999, 159 (06) :1843-1848
[27]   Inhaled mannitol for the treatment of mucociliary dysfunction in patients with bronchiectasis: Effect on lung function, health status and sputum [J].
Daviskas, E ;
Anderson, SD ;
Gomes, K ;
Briffa, P ;
Cochrane, B ;
Chan, HK ;
Young, IH ;
Rubin, BK .
RESPIROLOGY, 2005, 10 (01) :46-56
[28]   The 24-h effect of mannitol on the clearance of mucus in patients with bronchiectasis [J].
Daviskas, E ;
Anderson, SD ;
Eberl, S ;
Chan, HK ;
Young, IH .
CHEST, 2001, 119 (02) :414-421
[29]   Effect of mannitol and repetitive coughing on the sputum properties in bronchiectasis [J].
Daviskas, Evangelia ;
Anderson, Sandra D. ;
Young, Iven H. .
RESPIRATORY MEDICINE, 2010, 104 (03) :371-377
[30]   Inhaled tobramycin in non-cystic fibrosis patients with bronchiectasis and chronic bronchial infection with Pseudomonas aeruginosa [J].
Drobnic, ME ;
Suñé, P ;
Montoro, JB ;
Ferrer, A ;
Orriols, R .
ANNALS OF PHARMACOTHERAPY, 2005, 39 (01) :39-44