A mild and efficient dehydrogenation of indolines

被引：35

作者：

Tilstam, U ^{[1
]}

Harre, M ^{[1
]}

Heckrodt, T ^{[1
]}

Weinmann, H ^{[1
]}

机构：

[1] Schering AG Berlin, Proc Res, D-13342 Berlin, Germany

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 32期

关键词：

D O I：

10.1016/S0040-4039(01)00986-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new mild and efficient dehydrogenation of indolines to indoles has been developed. For the dehydrogenation trichloroisocyanuric acid is used in combination with DBU. After work-up with sodium hydrogen sulfite it was possible to obtain indole in an almost quantitative yield. The new method is also suitable for indolines bearing electron withdrawing or electron donating groups. Under the reaction conditions no ring chlorination was observed. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：5385 / 5387

页数：3

共 11 条

[1]

[Anonymous], 1999, ULLMANS ENCY IND CHE

[2] CATALYTIC-OXIDATION OF SECONDARY-AMINES WITH TETRA-N-PROPYLAMMONIUM PERRUTHENATE [J].