Multidisciplinary Care of Patients with Intrahepatic Cholangiocarcinoma: Updates in Management

被引:33
作者
Lafaro, Kelly J. [1 ]
Cosgrove, David [2 ]
Geschwind, Jean-Francois H. [3 ]
Kamel, Ihab [3 ]
Herman, Joseph M. [4 ]
Pawlik, Timothy M. [1 ]
机构
[1] Johns Hopkins Univ Hosp, Dept Surg, Baltimore, MD 21287 USA
[2] Johns Hopkins Univ Hosp, Dept Oncol, Baltimore, MD 21287 USA
[3] Johns Hopkins Univ Hosp, Dept Radiol, Baltimore, MD 21287 USA
[4] Johns Hopkins Univ Hosp, Dept Radiat Oncol, Baltimore, MD 21287 USA
关键词
C VIRUS-INFECTION; TRANSCATHETER ARTERIAL CHEMOEMBOLIZATION; BILIARY-TRACT CARCINOMA; LONG-TERM SURVIVAL; PHASE-II TRIAL; RADIOFREQUENCY ABLATION; PROGNOSTIC-FACTORS; RETROSPECTIVE ANALYSIS; SURGICAL-TREATMENT; RISK-FACTORS;
D O I
10.1155/2015/860861
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Cholangiocarcinoma is a highly fatal primary cancer of the bile ducts which arises from malignant transformation of bile duct epithelium. While being an uncommon malignancy with an annual incidence in the United States of 5000 new cases, the incidence has been increasing over the past 30 years and comprises 3% of all gastrointestinal cancers. Cholangiocarcinoma can be classified into intrahepatic (ICC) and extrahepatic (including hilar and distal bile duct) according to its anatomic location within the biliary tree with respect to the liver. This paper reviews the management of ICC, focusing on the epidemiology, risk factors, diagnosis, and surgical and nonsurgical management.
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页数:14
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