CdSe/ZnS quantum dot-Cytochrome c bioconjugates for selective intracellular O2•- sensing

被引：49

作者：

Li, Da-Wei ^{[1
,2
]}

Qin, Li-Xia ^{[1
,2
]}

Li, Yang ^{[1
,2
]}

Nia, Raheleh Partovi ^{[3
]}

Long, Yi-Tao ^{[1
,2
]}

Chen, Hong-Yuan ^{[4
]}

机构：

[1] E China Univ Sci & Technol, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China

[2] E China Univ Sci & Technol, Dept Chem, Shanghai 200237, Peoples R China

[3] Univ Western Ontario, London, ON N6A 3K7, Canada

[4] Nanjing Univ, Dept Chem, Nanjing 210093, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 30期

基金：

中国国家自然科学基金;

关键词：

LIVE CELLS; MODIFIED ELECTRODES; IN-VIVO; SUPEROXIDE; SEMICONDUCTOR; SENSORS; GENERATION; INTERFACE; RADICALS;

D O I：

10.1039/c1cc13160e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We demonstrate that the coupling system of negatively capped CdSe/ZnS QDs with an oxidized Cytochrome c (Cyt c) is capable of the fluorescent imaging of a superoxide radical (O-2(center dot-)) with high sensitivity and specificity in living cells, without interference from other Reactive Oxygen Species (ROS) or relevant intracellular components.

引用

页码：8539 / 8541

页数：3

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