Dry-media one-pot syntheses of fluorinated-2,3-dihydro-1,5-benzothiazepines under microwave activation

被引：66

作者：

Dandia, A ^{[1
]}

Sati, M

Loupy, A

机构：

[1] Univ Rajasthan, Dept Chem, Jaipur 302004, Rajasthan, India

[2] Univ Paris 11, Lab React Select Supports, ICMMO, UMR 8615, F-91405 Orsay, France

来源：

GREEN CHEMISTRY | 2002年 / 4卷 / 06期

关键词：

D O I：

10.1039/b207004a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new efficient and environmentally friendly green chemistry procedure for the syntheses of a series of 8-substituted-2-carboxy-2,3-dihydro-1,5-benzothiazepines under microwave irradiation and solvent-free conditions is described. Results were compared with those obtained following classical thermal method. A judicious choice of the reaction conditions allowed the final products 4a-f to be generated in excellent yields in a one-step procedure, whereas experiments under thermal conditions led to benzothiazepines along with other products in lower yields with tedious work-up.

引用

页码：599 / 602

页数：4

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