Tau phosphorylation is more closely associated with amyloid-β plaques than with tau neurofibrillary tangles

被引:0
作者
Vermeiren, M. [1 ]
Therriault, J. [1 ,2 ]
Servaes, S. [1 ,2 ]
Lussier, F. [1 ,2 ]
Tissot, C. [1 ,2 ]
Pascoal, T. [3 ,4 ]
Chamoun, M. [1 ,2 ]
Bezgin, G. [1 ,2 ]
Benedet, A. [5 ,6 ]
Ashton, N. [6 ]
Karikari, T. [5 ,6 ]
Lantero-Rodriguez, J. [5 ,6 ]
Stevenson, J. [1 ,2 ]
Rahmouni, N. [1 ,2 ]
Kunach, P. [1 ,2 ]
Wang, T. [1 ,2 ]
Fernandez-Arias, J. [1 ,2 ]
Massarweh, G. [7 ]
Vitali, P. [2 ]
Soucy, J. [2 ]
Saha-Chaudhuri, P. [8 ,9 ]
Blennow, K. [5 ,6 ]
Zetterberg, H. [5 ,6 ]
Gauthier, S. [1 ,2 ]
Rosa-Neto, P. [1 ,2 ]
机构
[1] McGill Res Ctr Studies Aging, Translat Neuroimaging Lab, Verdun, PQ, Canada
[2] McGill Univ, Fac Med, Dept Neurol & Neurosurg, Montreal, PQ, Canada
[3] Univ Pittsburgh, Sch Med, Dept Neurol, Pittsburgh, PA 15261 USA
[4] Univ Pittsburgh, Sch Med, Dept Psychiat, Pittsburgh, PA USA
[5] Sahlgrens Univ Hosp, Clin Neurochem Lab, Molndal, Sweden
[6] Univ Gothenburg, Sahlgrenska Acad, Inst Neurosci & Physiol, Dept Psychiat & Neurochem, Gothenburg, Sweden
[7] McGill Univ, Dept Radiochem, Montreal, PQ, Canada
[8] McGill Univ, Dept Epidemiol & Biostat, Montreal, PQ, Canada
[9] Univ Vermont, Dept Math & Stat, Burlington, VT 05405 USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
558
引用
收藏
页码:267 / 267
页数:1
相关论文
共 50 条
[21]   Chip colocalizes with phosphorylated tau in neurofibrillary tangles in AD brain [J].
Shin, Y ;
McLean, PJ ;
Hyman, BT .
NEUROBIOLOGY OF AGING, 2004, 25 :S431-S431
[22]   Visualization of six tau isoforms in Alzheimer's neurofibrillary tangles [J].
Mori, H ;
Arawaka, S ;
Tomiyama, T ;
Izumiyama, N ;
Takubo, K ;
Lee, G .
NEUROBIOLOGY OF AGING, 2002, 23 (01) :S497-S497
[23]   Cortical microinfarcts are related to cerebral amyloid angiopathy rather than to senile plaques or neurofibrillary tangles [J].
Okamoto, Y. ;
Ihara, M. ;
Ito, H. ;
Yamamoto, T. ;
Tomimoto, H. ;
Takahashi, R. .
BRAIN PATHOLOGY, 2010, 20 :17-17
[24]   RELATIVE ABUNDANCE OF TAU AND NEUROFILAMENT EPITOPES IN HIPPOCAMPAL NEUROFIBRILLARY TANGLES [J].
SCHMIDT, ML ;
LEE, VMY ;
TROJANOWSKI, JQ .
AMERICAN JOURNAL OF PATHOLOGY, 1990, 136 (05) :1069-1075
[25]   Imaging β-amyloid plaques and neurofibrillary tangles in the aging human brain [J].
Mathis, CA ;
Wang, Y ;
Klunk, WE .
CURRENT PHARMACEUTICAL DESIGN, 2004, 10 (13) :1469-1492
[26]   Tau Phosphorylation-Much More than a Biomarker [J].
Maeda, Sumihiro ;
Mucke, Lennart .
NEURON, 2016, 92 (02) :265-267
[27]   Tau phosphorylation, tangles, and neurodegeneration: The chicken or the egg? [J].
Geschwind, DH .
NEURON, 2003, 40 (03) :457-460
[28]   Amyloid precursor protein reduction enhances the formation of neurofibrillary tangles in a mutant tau transgenic mouse model [J].
Dries, Virginie Vanden ;
Stygelbout, Virginie ;
Pierrot, Nathalie ;
Yilmaz, Zehra ;
Suain, Valerie ;
De Decker, Robert ;
Buee, Luc ;
Octave, Jean-Noel ;
Brion, Jean-Pierre ;
Leroy, Karelle .
NEUROBIOLOGY OF AGING, 2017, 55 :202-212
[29]   Role of TREM2 in Alzheimer's Disease and its Consequences on β-Amyloid, Tau and Neurofibrillary Tangles [J].
Singh, Anurag K. ;
Mishra, Gaurav ;
Maurya, Anand ;
Awasthi, Rajendra ;
Kumari, Komal ;
Thakur, Abhimanyu ;
Rai, Arati ;
Rai, Gopal Kumar ;
Sharma, Bhupesh ;
Kulkarni, Giriraj T. ;
Singh, Santosh Kumar .
CURRENT ALZHEIMER RESEARCH, 2019, 16 (13) :1216-1229
[30]   beta PP and tau interaction - A possible link between amyloid and neurofibrillary tangles in Alzheimer's disease [J].
Giaccone, G ;
Pedrotti, B ;
Migheli, A ;
Verga, L ;
Perez, J ;
Racagni, G ;
Smith, MA ;
Perry, G ;
DeGioia, L ;
Selvaggini, C ;
Salmona, M ;
Ghiso, J ;
Frangione, B ;
Islam, K ;
Bugiani, O ;
Tagliavini, F .
AMERICAN JOURNAL OF PATHOLOGY, 1996, 148 (01) :79-87