Photochemical control of biological processes

被引：172
作者：
Young, Douglas D. [1 ]
Deiters, Alexander [1 ]
机构：
[1] N Carolina State Univ, Dept Chem, Raleigh, NC 27695 USA
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2007年 / 5卷 / 07期
关键词：
D O I：
10.1039/b616410m
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Photochemical regulation of biological processes offers a high level of control to study intracellular mechanisms with unprecedented spatial and temporal resolution. This report summarizes the advances made in recent years, focusing predominantly on the in vivo regulation of gene function using irradiation with UV light. The majority of the described applications entail the utilization of photocaging groups installed either on a small molecule modulator of biomolecular function or directly on a biological macromolecule itself.
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收藏
页码：999 / 1005
页数：7
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