Why So Few Randomized Trials in Pediatric Critical Care Medicine? Ask the Trialists

被引:2
作者
Randolph, Adrienne G. [1 ,2 ,3 ]
机构
[1] Boston Childrens Hosp, Dept Anesthesiol Perioperat & Pain Med, Div Crit Care Med, Boston, MA 02115 USA
[2] Harvard Med Sch, Dept Anaesthesia, Boston, MA 02115 USA
[3] Harvard Med Sch, Dept Pediat, Boston, MA 02115 USA
关键词
pediatric critical care; randomized controlled trials; research networks; survey; CLINICAL-TRIALS; CHILDREN; FEASIBILITY;
D O I
10.1097/PCC.0000000000001156
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
引用
收藏
页码:486 / 487
页数:2
相关论文
共 9 条
[1]   High-Quality Randomized Controlled Trials in Pediatric Critical Care: A Survey of Barriers and Facilitators [J].
Duffett, Mark ;
Choong, Karen ;
Foster, Jennifer ;
Meade, Maureen ;
Menon, Kusum ;
Parker, Melissa ;
Cook, Deborah J. .
PEDIATRIC CRITICAL CARE MEDICINE, 2017, 18 (05) :405-413
[2]   Randomized controlled trials in pediatric critical care: a scoping review [J].
Duffett, Mark ;
Choong, Karen ;
Hartling, Lisa ;
Menon, Kusum ;
Thabane, Lehana ;
Cook, Deborah J. .
CRITICAL CARE, 2013, 17 (05)
[3]   Hypoglycemia and Risk of Death in Critically Ill Patients [J].
Finfer, Simon ;
Liu, Bette ;
Chittock, Dean R. ;
Norton, Robyn ;
Myburgh, John A. ;
McArthur, Colin ;
Mitchell, Imogen ;
Foster, Denise ;
Dhingra, Vinay ;
Henderson, William R. ;
Ronco, Juan J. ;
Bellomo, Rinaldo ;
Cook, Deborah ;
McDonald, Ellen ;
Dodek, Peter ;
Hebert, Paul C. ;
Heyland, Daren K. ;
Robinson, Bruce G. .
NEW ENGLAND JOURNAL OF MEDICINE, 2012, 367 (12) :1108-1118
[4]   Impregnated central venous catheters for prevention of bloodstream infection in children (the CATCH trial): a randomised controlled trial [J].
Gilbert, Ruth E. ;
Mok, Quen ;
Dwan, Kerry ;
Harron, Katie ;
Moitt, Tracy ;
Millar, Mike ;
Ramnarayan, Padmanabhan ;
Tibby, Shane M. ;
Hughes, Dyfrig ;
Gamble, Carrol .
LANCET, 2016, 387 (10029) :1732-1742
[5]   No child left behind: Enrolling children and adults simultaneously in critical care randomized trials [J].
Halpern, Scoff D. ;
Randolph, Adrienne G. ;
Angus, Derek C. .
CRITICAL CARE MEDICINE, 2009, 37 (09) :2638-2641
[6]   Research ethics board approval for an international thromboprophylaxis trial [J].
Lutz, Kristina ;
Wilton, Kelly ;
Zytaruk, Nicole ;
Julien, Lisa ;
Hall, Richard ;
Harvey, Johanne ;
Skrobik, Yoanna ;
Vlahakis, Nicholas ;
Meade, Laurie ;
Matte, Andrea ;
Meade, Maureen ;
Burns, Karen ;
Albert, Martin ;
Cash, Bronwyn Barlow ;
Vallance, Shirley ;
Klinger, James ;
Heels-Ansdell, Diane ;
Cook, Deborah .
JOURNAL OF CRITICAL CARE, 2012, 27 (03) :225-231
[7]   Pragmatic trials in critically ill children are CATCHing on [J].
Randolph, Adrienne G. .
LANCET, 2016, 387 (10029) :1697-1698
[8]   The feasibility of conducting clinical trials in infants and children with acute respiratory failure [J].
Randolph, AG ;
Meert, KL ;
O'Neil, ME ;
Hanson, JH ;
Luckett, PM ;
Arnold, JH ;
Gedeit, RG ;
Cox, PN ;
Roberts, JS ;
Venkataraman, ST ;
Forbes, PW ;
Cheifetz, IM .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2003, 167 (10) :1334-1340
[9]   Acute lung injury in children: Therapeutic practice and feasibility of international clinical trials [J].
Santschi, Miriam ;
Jouvet, Philippe ;
Leclerc, Francis ;
Gauvin, France ;
Newth, Christopher J. L. ;
Carroll, Christopher L. ;
Flori, Heidi ;
Tasker, Robert C. ;
Rimensberger, Peter C. ;
Randolph, Adrienne G. .
PEDIATRIC CRITICAL CARE MEDICINE, 2010, 11 (06) :681-689