Gut-Brain Interactions Implications for a Role of the Gut Microbiota in the Treatment and Prognosis of Anorexia Nervosa and Comparison to Type I Diabetes

被引:8
作者
Igudesman, Darla [1 ]
Sweeney, Megan [1 ]
Carroll, Ian M. [1 ]
Mayer-Davis, Elizabeth J. [1 ]
Bulik, Cynthia M. [1 ,2 ,3 ]
机构
[1] Univ N Carolina, Dept Nutr, 135 Dauer Dr, Chapel Hill, NC 27599 USA
[2] Univ N Carolina, Dept Psychiat, 101 Manning Dr, Chapel Hill, NC 27599 USA
[3] Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden
基金
瑞典研究理事会; 美国国家卫生研究院;
关键词
Anorexia nervosa; Diabetes; Microbiome; Microbiota; Metabolism; RESTING ENERGY-EXPENDITURE; EATING-DISORDERS; METHANOBREVIBACTER-SMITHII; INSULIN-RESISTANCE; WEIGHT-LOSS; FOLLOW-UP; INTESTINAL MICROBIOTA; AUTOANTIBODIES; ADOLESCENTS; PREVALENCE;
D O I
10.1016/j.gtc.2019.04.003
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Anorexia nervosa has poor prognosis and treatment outcomes and is influenced by genetic, metabolic, and psychological factors. Gut microbes interact with gut physiology to influence metabolism and neurobiology, although potential therapeutic benefits remain unknown. Type 1 diabetes is linked to anorexia nervosa through energy dysregulation, which in both disease states is related to the gut microbiota, disordered eating, and genetics.
引用
收藏
页码:343 / +
页数:15
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