Processing Speed Versus Working Memory: Contributions to an Information-Processing Task in Multiple Sclerosis

被引:29
作者
Genova, Helen M. [1 ,2 ]
Lengenfelder, Jeannie [1 ,2 ]
Chiaravalloti, Nancy D. [1 ,2 ]
Moore, Nancy B. [1 ]
DeLuca, John [1 ,2 ]
机构
[1] Kessler Fdn, Res Ctr, Neuropsychol & Neurosci Lab, W Orange, NJ 07052 USA
[2] Univ Med & Dent New Jersey, New Jersey Med Sch, Newark, NJ 07103 USA
关键词
cognitive rehabilitation; Keeping Track Task; multiple sclerosis; processing speed; working memory; OPERATIONAL CAPACITIES; COGNITIVE IMPAIRMENT; DIAGNOSTIC-CRITERIA; ADULT AGE; DEFICITS; PERFORMANCE; EFFICIENCY; GUIDELINES;
D O I
10.1080/09084282.2011.643951
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Individuals with multiple sclerosis (MS) often experience cognitive impairments in information processing. However, the relative contributions of processing speed abilities and working memory abilities to information-processing tasks are not yet fully understood. The current study examined the extent to which processing speed and/or working memory abilities contributed to an information-processing task, the Keeping Track Task (KTT). Forty-nine individuals with MS were given tests to assess processing speed and working memory, as well as the KTT. Regression analyses indicated that in the MS group, processing speed abilities accounted for the majority of the explained variance in KTT performance. The findings suggest that processing speed plays a significant role on KTT performance in MS. Implications for cognitive rehabilitation treatments aimed at improving processing speed abilities in MS are discussed.
引用
收藏
页码:132 / 140
页数:9
相关论文
共 57 条
[1]   Cognitive patterns and progression in multiple sclerosis: construction and validation of percentile curves [J].
Achiron, A ;
Polliack, M ;
Rao, SM ;
Barak, Y ;
Lavie, M ;
Appelboim, N ;
Harel, Y .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2005, 76 (05) :744-749
[2]   The relationship of APOE genotype to neuropsychological performance in long-term cancer survivors treated with standard dose chemotherapy [J].
Ahles, TA ;
Saykin, AJ ;
Noll, WW ;
Furstenberg, CT ;
Guerin, S ;
Cole, B ;
Mott, LA .
PSYCHO-ONCOLOGY, 2003, 12 (06) :612-619
[3]  
[Anonymous], 1993, J AM GERIATR SOC
[4]  
Archibald CJ, 2000, J CLIN EXP NEUROPSYC, V22, P686, DOI 10.1076/1380-3395(200010)22:5
[5]  
1-9
[6]  
FT686
[7]   Posterior fossa lesion volume and slowed information processing in multiple sclerosis [J].
Archibald, CJ ;
Wei, XC ;
Scott, JN ;
Wallace, CJ ;
Zhang, Y ;
Metz, LM ;
Mitchell, JR .
BRAIN, 2004, 127 :1526-1534
[8]   Speed of presentation influences story recall in college students and persons with multiple sclerosis [J].
Arnett, PA .
ARCHIVES OF CLINICAL NEUROPSYCHOLOGY, 2004, 19 (04) :507-523
[9]   Working memory [J].
Baddeley, Alan .
CURRENT BIOLOGY, 2010, 20 (04) :R136-R140
[10]  
Baddeley A., 1994, Neuropsychology, V8, P485, DOI [10.1037/0894-4105.8.4.485, DOI 10.1037/0894-4105.8.4.485]