Effect of sugar-feeding strategies on astaxanthin production by Xanthophyllomyces dendrorhous

被引:20
作者
Hu, ZC [1 ]
Zheng, YG [1 ]
Wang, Z [1 ]
Shen, YC [1 ]
机构
[1] Zhejiang Univ Technol, Inst Bioengn, State Key Lab Breeding Base Green Chem Synth Tech, Hangzhou 310014, Peoples R China
关键词
astaxanthin; fed-batch fermentation; Xanthophyllomyces dendrorhous;
D O I
10.1007/s11274-004-5566-x
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Astaxanthin, a main carotenoid pigment, has a strong antioxidant activity. The effects of sugar-feeding strategies on astaxanthin production by Xanthophyllomyces dendrorhous fed-batch fermentation were studied. Sugar was added instantaneously to a 30 l fermentor at various discrete time instants (pulse-feeding), or continuously to the fermentor to maintain the constant sugar concentration. Pulse-feeding experiments were initiated with sugar concentrations from 30 to 50 g/l, and then one, two, three and four feedings were made. The results showed that optimal sugar feeding depended on feeding time and pulse sugar feeding was the best among all experiments, in which a significant increase (54.9%) in production of astaxanthin was achieved at 132 h in a pulse fed-batch process compared with a batch process.
引用
收藏
页码:771 / 775
页数:5
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