Variability of Platelet Reactivity on Antiplatelet Therapy in Neurointervention Procedure

被引：14

作者：

Yi, Ho Jun ^{[1
]}

Hwang, Gyojun ^{[1
]}

Lee, Byoung Hun ^{[1
]}

机构：

[1] Hallym Univ, Coll Med, Dept Neurosurg, Hangang Sacred Heart Hosp, 12 Beodeunaru Ro 7 Gil, Seoul 07247, South Korea

来源：

JOURNAL OF KOREAN NEUROSURGICAL SOCIETY | 2019年 / 62卷 / 01期

关键词：

Aspirin; Clopidogrel; Platelet aggregation inhibitors; Platelet function tests; ASPIRIN RESISTANCE; COIL EMBOLIZATION; THROMBOEMBOLIC COMPLICATIONS; CLOPIDOGREL RESISTANCE; ENDOVASCULAR TREATMENT; STENT THROMBOSIS; PRASUGREL; ANEURYSMS; RISK; INHIBITION;

D O I：

10.3340/jkns.2018.0151

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

As more intracranial aneurysms and other cerebrovascular pathologies are treated with neurointervention procedure, thromboembolic events that frequently lead to serious neurological deficit or fatal outcomes are increasing. In order to prevent the thromboembolic events, antiplatelet therapy is used in most procedures including coil embolization, stenting, and flow diversion. However, because of variable individual pharmacodynamics responses to antiplatelet drugs, especially clopidogrel, it is difficult for clinicians to select the adequate antiplatelet regimen and its optimal dose. This article reviews the neurointervention literature related to antiplatelet therapy and suggests a strategy for tailoring antiplatelet therapy in individual patients undergoing neurointervention based on the results of platelet function testing.

引用

收藏

页码：3 / 9

页数：7

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