Effect of transmural pressure on constrictor reactions of caudal artery in hypotensive and hypertensive rats

被引：0

作者：

Vlasova, MA ^{[1
]}

Borovik, AS ^{[1
]}

Timin, EN ^{[1
]}

Tarasova, OS ^{[1
]}

Rodionov, IM ^{[1
]}

机构：

[1] AV Vishnevskii Surg Inst, Lab Cybernet, Moscow 113093, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2003年 / 136卷 / 01期

基金：

俄罗斯基础研究基金会;

关键词：

rats; norepinephrine; regional hypotension; caudal artery; endothelium;

D O I：

10.1023/A:1026076510582

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Clipping of the abdominal aorta distally to the renal arteries produces a persistent decrease in blood pressure in hindquarter vessels by 35-40%. On week 6-7 postoperation, the reactions of the caudal artery perfused in vitro under constant pressure to norepinephrine were studied. At transmural pressure of 150 min Hg, the vascular responses in hypotensive rats were reduced compared to those in non-notensive control. By contrast, the responses of hypertensive vessels were more pronounced at 75 mm Hg even after deendothelization.

引用

页码：30 / 33

页数：4

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