Rat feeding trials: A comprehensive assessment of contaminants in both genetically modified maize and resulting pellets

被引：3

作者：

Chereau, S. ^{[1
]}

Rogowsky, P. ^{[2
]}

Laporte, B. ^{[3
]}

Coumoul, X. ^{[4
]}

Moing, A. ^{[5
]}

Priymenko, N. ^{[3
]}

Steinberg, P. ^{[6
,8
]}

Wilhelm, R. ^{[7
]}

Schiemann, J. ^{[7
]}

Salles, B. ^{[3
]}

Richard-Forget, F. ^{[1
]}

机构：

[1] INRA, UR MycSA 1264, Ctr INRA Nouvelle Aquitaine Bordeaux, 71 Av Edouard Bourlaux, F-33140 Villenave Dornon, France

[2] Univ Lyon, CNRS, INRA, UCB Lyon1,ENS Lyon,Lab Reprod & Dev Plantes, F-69000 Lyon, France

[3] Univ Toulouse, INRA, ENVT, INP,UPS,Toxalim Res Ctr Food Toxicol, F-31027 Toulouse, France

[4] Univ Paris 05, INSERM, UMRS1124, Toxicol Pharmacol & Signalisat Cellulaire, F-75000 Paris, France

[5] Univ Bordeaux, INRA, Biol Fruit & Pathol UMR1332, Plateforme Metabolome Bordeaux MetaboHUB,Ctr INRA, 71 Av Edouard Bourlaux, F-33140 Villenave Dornon, France

[6] Univ Vet Med Hannover, Inst Food Toxicol & Analyt Chem, Bischofsholer Damm 15, D-3073 Hannover, Germany

[7] Julius Kuhn Inst, Fed Res Ctr Cultivated Plants, Inst Biosafety Plant Biotechnol, Erwin Baur Str 27, D-06484 Quedlinburg, Germany

[8] Max Rubner Inst, Fed Res Inst Nutr & Food, Haid & Neu Str 9, D-76131 Karlsruhe, Germany

来源：

FOOD AND CHEMICAL TOXICOLOGY | 2018年 / 121卷

关键词：

GM maize; GM pellets; Mycotoxins; Heavy metals; Pesticides; FOOD CONTAMINANTS; SAFETY ASSESSMENT; MYCOTOXINS; TOXICITY; EXPOSURE; GENE;

D O I：

10.1016/j.fct.2018.09.049

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

We analyzed a comprehensive set of contaminants in MON810 and NK603 genetically modified (GM) maize, and their non-GM counterparts, used in a rat feeding study (the GM090 + project). Both the maize grains and the manufactured pellets were characterized. Only minor differences in contaminant levels between GM and corresponding non-GM harvests were evidenced. Fumonisin and deoxynivalenol mycotoxins were the pollutants present in the highest amounts, with concentrations that were however largely below acceptance reference values. Our data reporting slightly lower levels of fumonisin in MON810 compared to its non-GM counterpart corroborate the lower susceptibility of insect resistant Bt maize to fumonisin-producing fungi. Traces of glyphosate (0.016 mg/kg) were evidenced in grains from NK603 treated crops. Regarding the pellets, analysis of more than 650 potentially toxic substances revealed low amounts of various mycotoxins, pesticides and heavy metals. Concentrations of contaminants quantified in the pellets were however far below the maximum level of residues values set by regulatory agencies, and no substantial differences in contaminants between GM and non GM pellets were observed. Moreover, when comparing the contamination status of grains and pellets, we demonstrate yet again that characterizing the grains is actually not sufficient to foresee the quality of the produced pellets.

引用

页码：573 / 582

页数：10